Killing John to save Mary: a defence of the moral distinction between killing and letting die [PDF]
, 2007 Introduction This paper defends the moral significance of the distinction between killing and letting die. In the first part of the paper, I consider and reject Michael Tooley’s argument that initiating a causal process is morally equivalent to ...
Frowe, H.
core
Public HMDs: Modeling and Understanding User Behavior Around Public Head-Mounted Displays [PDF]
, 2018 Head-Mounted Displays (HMDs) are becoming ubiquitous; we are starting to see them deployed in public for different purposes. Museums, car companies and travel agencies use HMDs to promote their products. As a result, situations arise where users use them
Brignull Harry +3 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Biodiversity of aquatic insects in relation to physico-chemical parameters of Shekh Turab stream
Passer Journal, 2019 Ecological integrity and their properties of any aquatic environment are important to monitor its stability and any change to the ecological system. The current work was undertaken to study the community of aquatic insects and physio-chemical variables ...
Faris Zaidan Jarjees +2 more
doaj +1 more source
PERANAN ORGANISASI PASSER (PAGUYUBAN AJEN SUNDA SEJA RAHARJA) DALAM MEMBINA KARAKTER KEPEDULIAN MASYARAKAT [PDF]
, 2016 Penelitian ini dilatarbelakangi realita munculnya beberapa organisasi kemasyarakatan yang tidak sebanding antara kuantitas dan kualitasnya sebagai organisasi pemberdayaan masyarakat.Organisasi kemasyarakatan yang terbentuk mengalami disorientasi ...
Bachtiar, Yusup
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Design strategies for low embodied energy and greenhouse gases in buildings: analyses of the IEA Annex 57 case studies [PDF]
, 2014 This paper introduces the IEA Annex 57 case study method, consisting of a format for describing individual case studies and an evaluation matrix covering all case studies.
Birgisdottir, H. +8 more
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David Hume's Reductionist Epistemology of Testimony [PDF]
, 1998 David Hume advances a reductionist epistemology of testimony: testimonial beliefs are justified on the basis of beliefs formed from other sources. This reduction, however, has been misunderstood.
Faulkner, P.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source