Results 81 to 90 of about 664,076 (315)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

SHADES OF PASSING: THE DIALECTIC OF IDENTITY IN PHILIP ROTH’S THE HUMAN STAIN AND WILLIAM FAULKNER’S LIGHT IN AUGUST [PDF]

open access: yesUniversity of Bucharest Review. Literary and Cultural Studies Series, 2022
The paper takes a closer look at the phenomenon of racial passing as form of cultural transition: as transformation of identity, i.e. as changing of the Self in William Faulkner’s Light in August and Philip Roth’s The Human Stain.
Sonja Novak
doaj  

Passing tones and musical meaning

open access: yes, 1955
Michigan State University\u201a\uc4\uf4s Continuing Education Services, in cooperation with the College of Arts and Science\u201a\uc4\uf4s Department of Music, presents \u201a\uc4\uf2Passing Notes,\u201a\uc4\uf9 a weekly series dedicated to providing ...
WKAR-TV (Television station : East Lansing, Mich. : 1954-1958)   +2 more
core  

Indirect Purchasers, Passing-On and the New Directive on Competition Law Damages

open access: yes, 2014
This article aims to report and to analyse the approach chosen in the upcoming directive on damages for a breach of competition law, and accompanying instruments, to the position of indirect purchasers.
Strand, Magnus,
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Race in the Marketplace: Postmodern Passing and Ali G

open access: yes, 2014
The concern of this essay is to use recent critical disputes on balckface as a backdrop for examining how postmodern racial passing (as a form of racial morphing) in the visual media of film and television – with specific reference to the fictional ...
Mendes, Ana Cristina
core   +2 more sources

Passing the test [PDF]

open access: yesNature, 2007
What role should the federal government have in pre-college science education? David Goldston looks at why the US Congress is acting now to help define that.
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Pengaruh Penggunaan Model Problem Based Learning Terhadap Keterampilan Passing Dalam Permainan Futsal

open access: yesJuara, 2018
Futsal merupakan olahraga yang dinamis dikarenakan bola bergulir secara cepat dari kaki ke kaki, dimana para pemainnya dituntut untuk selalu bergerak dan dibutuhkan keterampilan yang baik dan determinasi yang tinggi, dan tidak salah lagi futsal digemari ...
Beni Hamzah, Oman Hadiana
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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