Results 21 to 30 of about 27,115 (235)

Why letting die instead of killing? Choosing active euthanasia on moral grounds [PDF]

open access: yes, 2018
Ever since the debate concerning euthanasia was ignited, the distinction between active and passive euthanasia – or, letting die and killing – has been marked as one of its key issues.
Protopapadakis, Evangelos
core   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

open access: yesAdvanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen   +5 more
wiley   +1 more source

A Critical Outlook on Rosenberg’s Theory of Euthanaisia [PDF]

open access: yesPizhūhish/hā-yi Falsafī- Kalāmī, 2017
In his book, while referring to anti-euthanasia arguments such as "prima facie right to life", "possibility of arbitrary encroachments", and "venerability of moral independence", Rosenberg draws a careful sketch of pro-euthanasia arguments including ...
Reza Akbari, Seyyed Ali Reza Hodaei
doaj   +1 more source

Euthanasia, or Mercy Killing [PDF]

open access: yes, 2019
Sadly, there are people in very bad medical conditions who want to die. They are in pain, they are suffering, and they no longer find their quality of life to be at an acceptable level anymore. When people like this are kept alive by
Nobis, Nathan
core  

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

open access: yesAdvanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann   +15 more
wiley   +1 more source

Euthanasia in Africa: A scoping review of empirical evidence

open access: yesHealth Science Reports, 2023
Background and Aims The core ethical perplexity is that physician‐assisted suicide and euthanasia (PAS/E) contradicts the core value of medical practice which is about the duty of care to preserve life.
Jimoh Amzat   +3 more
doaj   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

open access: yesAdvanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang   +11 more
wiley   +1 more source

The Total Artificial Heart and the Dilemma of Deactivation [PDF]

open access: yes, 2016
It is widely believed to be permissible for a physician to discontinue any treatment upon the request of a competent patient. Many also believe it is never permissible for a physician to intentionally kill a patient.
Bronner, Ben
core   +1 more source

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

open access: yesAdvanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han   +10 more
wiley   +1 more source

Aruna Shanbaug. A Case Study in Compassion, Dignity, and the Ethics of Euthanasia

open access: yesJournal of Legal Studies
The case of Aruna Shanbaug is a landmark case in Indian jurisprudence that significantly influenced the debate surrounding the right to die with dignity.
Navin Kumar
doaj   +1 more source

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