Results 131 to 140 of about 19,633,862 (302)
Advanced Materials, EarlyView.Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello +5 more
wiley +1 more source
Nuclear Engineering and TechnologyPassive safety systems are integrated into the latest generation of Light Water Reactors (LWRs), including small modular reactors. This paper employs the US-NRC TRACE thermal hydraulic code to examine the performance of a passive safety condenser known ...
Omar S. Al-Yahia +2 more
doaj +1 more source
Interfacial Failure and Self‐Healing in Solid‐State Batteries
Advanced Materials, EarlyView.Dynamic interfacial self‐healing offers an adaptive route to mitigate coupled mechanical, chemical, and electrochemical degradation in solid‐state batteries. This review connects evolving interfacial failure mechanisms with physical‐flow, chemical‐restoration, stimuli‐responsive, and electric‐field‐assisted repair strategies, highlighting targeted self‐
Xinxin Zhu +8 more
wiley +1 more source
The 31st International System Safety Conference: Safety for the Long Run
, 2014 Boston, Massachusetts was the setting for the 31st International System Safety Conference, and in one of America’s oldest cities, attendees heard from some of the leaders in the field to map out safer paths into the future.
Editors, JSS
core
System Safety in Healthcare: Using System Engineering Principles to Decrease Preventable Deaths
, 2016 The popular theory that human error, such as making the wrong diagnosis, operating on the wrong body part or administering the wrong medication, in itself causes harm to patients may not always be completely true.
Raheja, Dev
core +1 more source
Artificial Intelligence Meets Micro/Nanorobotics
Advanced Materials, EarlyView.Artificial intelligence is transforming micro‐ and nanorobots from externally controlled, task‐specific machines into adaptive, autonomous systems. Machine learning, multimodal perception, digital twins, AI‐guided materials and geometry design enhance propulsion, localization, decision‐making, whichaccelerates clinical and environmental applications ...
Fatma M. Yurtsever +6 more
wiley +1 more source
Notes on Society History: A Historical View of System Safety Orthodoxy
, 2017 A Webster’s definition of “orthodoxy” is “a belief or a way of thinking that is accepted as true or correct.” The founding fathers of our Society were convinced that the System Safety Concept (SSC), as articulated by Chuck Miller and other visionaries of
Gordon, Rex
core +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
President's Message: Forging a Future for System Safety
, 2017 In my last couple of messages to the Society, I cited Andy Grove, former CEO of Intel, who, in his 1998 book, Only the Paranoid Survive, advanced the concept of the “strategic inflection point” (see figure), and then discussed its implications for our ...
Simmons, Rodney
core +1 more source
Advanced Materials, EarlyView.A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian +7 more
wiley +1 more source