Results 41 to 50 of about 471,677 (263)

Experimental Validation of Hydrogen Fuel-Cell and Battery-Based Hybrid Drive without DC-DC for Light Scooter under Two Typical Driving Cycles

open access: yesEnergies, 2021
Faced with key obstacles, such as the short driving range, long charging time, and limited volume allowance of battery-powered electric light scooters in Asian cities, the aim of this study is to present a passive fuel cell/battery hybrid system without ...
Zhiming Zhang, Jianan Tang, Tong Zhang
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The concept of the innovative power reactor

open access: yesNuclear Engineering and Technology, 2017
The Fukushima accident reveals the vulnerability of existing active nuclear power plant (NPP) design against prolonged loss of external electricity events.
Sang Won Lee   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Analysis on Target Detection and Classification in LTE Based Passive Forward Scattering Radar

open access: yesSensors, 2016
The passive bistatic radar (PBR) system can utilize the illuminator of opportunity to enhance radar capability. By utilizing the forward scattering technique and procedure into the specific mode of PBR can provide an improvement in target detection and ...
Raja Syamsul Azmir Raja Abdullah   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

On Passivity Analysis and Passivation of Event-Triggered Feedback Systems Using Passivity Indices

open access: yesIEEE Transactions on Automatic Control, 2017
While most of the work in the literature focuses on stability conditions for event-triggered systems, in this technical note we focus on passivity and passivation of event-triggered feedback interconnected systems of two input feed-forward output-feedback (IF-OF) passive systems.
Feng Zhu 0021   +2 more
openaire   +2 more sources

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Thermal Performance Evaluation of Phase Change Material-Integrated Triple-Glazed Windows Under Korean Climatic Conditions

open access: yesEnergies
Passive design strategies incorporating phase change materials (PCM) provide effective thermal energy storage, improve indoor comfort, and reduce building energy demand.
Kwanghyun Song   +4 more
doaj   +1 more source

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