Results 111 to 120 of about 793,583 (297)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Aging and Cancer, EarlyView.This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
Interactions of Organizational Culture and Collaboration in Working and Learning [PDF]
This paper reports the methodologies and findings of research done into learning processes in two diverse environments. The research focused on identifying factors that enable and facilitate social learning.
Ioan PASTOR
core
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Reading for the acquisition and use of information and as a literary experience. Method "CRACE"
Avances en Supervisión Educativa, 2009 El fomento de la lectura, un esfuerzo personal y colectivo ¿En qué medida una cierta crisis en el desarrollo de las capacidades y actitudes lectoras de nuestros alumnos es una de las causas que han contribuido a degradar la educación?
Fernando Carratalá Teruel
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
El Antiguo Testamento y la cultura
TheoRhēma, 2019 The article analyses the interaction between the ANE environment and Israelite culture. Four types of relations are addressed: rejection or prohibition, neutrality, acceptance and assimilation.
Laurențiu G. Ionescu
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Development and Validity and Reliability of an Instrument to Assess Patient’s Spiritual Well-Being
Journal of Multidisciplinary HealthcareChun-Kai Fang,1– 4 Sung-Yuan Cheng,5 Shih-Hsuan Pi,6,7 Ya-Li Wu,5 Keng-Chen Lin,5,8 Ruei-Yi Pan5 1Hospice and Palliative Care Center, MacKay Memorial Hospital, New Taipei, Taiwan; 2Department of Thanatology and Health Counseling, National Taipei ...
Fang CK +5 more
doaj