Results 121 to 130 of about 107,689 (246)

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Biodiversity resilience in a tropical rainforest. [PDF]

Nature
Metz T, Farwig N, Dormann CF, Schaefer HM, Guevara-Andino JE, Brehm G, Burneo S, Chao A, Chazdon RL, Colwell RK, Diniz UM, Donoso DA, Endara MJ, Erazo S, Escobar S, Falconí-López A, Feldhaar H, Villamarin MG, Grella N, Heer K, Heethoff M, Keller A, Landim AR, Leonhardt SD, Lopez ET, Marín-Armijos D, Müller J, Neira-Salamea K, Neuschulz EL, Pedersen KM, Rödel MO, Schleuning M, Schmitt T, Staab M, Tartara A, Tinoco BA, Tremlett CJ, Tschapka M, Unsicker S, Villa-Galaviz E, Blüthgen N.   +40 more
europepmc   +1 more source

An Integrated NLP‐ML Framework for Property Prediction and Design of Steels

Advanced Science, EarlyView.
This study presents a data‐driven framework that uses language‐processing techniques to interpret steel processing descriptions and machine‐learning models to predict mechanical properties. By organising complex process histories into meaningful groups and enabling rapid property forecasts, the work supports faster, more informed steel design through ...
Kiran Devraju, Adithya Umanath Rai, Jose Thomson, Marzie Ghorbani, Shujing Zhao, Nick Birbilis   +5 more
wiley   +1 more source

Partially mixed ration silages based on banana leaves, with and without tomato residue, in the diet of lambs under semi-arid conditions. [PDF]

Trop Anim Health Prod
Moreira Silva A, Portes Caldeira AS, Rigueira JPS, Vieira LKF, Gomes VM, Murta RM, Lúcia Dos Santos Oliveira L, Vieira E Silva F.   +7 more
europepmc   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Seasonal variation in meat quality of Angus steers raised in a Mediterranean forage-fed system: A farm case study. [PDF]

PLoS One
Bolletta V, Roscini V, Lilli E, Fodaroni C, Orlando JG, Mercati V, Valenti B, Pauselli M.   +7 more
europepmc   +1 more source

Pasture plants and pastures of New Zealand

, 1918
openaire   +3 more sources

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

Advanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu, Wenhao Zhang, Yifan Zhang, Yu He, Yi Du, Yiding Zhao, Chunmeng Yao, Shengyi Sun, Xiaoyan Sheng, Qian Gao, Chao Tong, Ling Shuai   +11 more
wiley   +1 more source

Long-Read Sequencing for Species-Level Resolution of the Equine Gut Microbiota Reveals the Need for Improved Databases. [PDF]

Animals (Basel)
Leduc L, Boucher L, Mach N, Leclère M, Costa M.   +4 more
europepmc   +1 more source