Results 161 to 170 of about 238,810 (340)

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

open access: yesAdvanced Science, EarlyView.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li   +13 more
wiley   +1 more source

Greenhouse gas balance and carbon footprint of beef cattle in three contrasting pasture-management systems in Brazil

open access: yes, 2017
E. Figueiredo   +6 more
semanticscholar   +1 more source

Bioprinted Tumor Microenvironment Models Reveal Immune Evasion and Guide CAR‐NK Therapeutic Strategies

open access: yesAdvanced Science, EarlyView.
This study presents a 3D embedded bioprinting platform that recapitulates key stromal features of the tumor microenvironment using fibroblasts and lung‐derived ECM. The model enables functional assessment of CAR‐NK cells and provides a versatile tool to support the development of next‐generation immunotherapeutic strategies against solid tumors ...
Dahong Kim   +10 more
wiley   +1 more source

Effect of pasture versus indoor feeding systems on raw milk composition and quality over an entire lactation.

open access: yesJournal of Dairy Science, 2016
T. O’Callaghan   +10 more
semanticscholar   +1 more source

Pasture-tree systems: effect on soil carbon accumulation

open access: yes, 2015
Determine the effect of established trees at varying densities on soil C concentration and mass to 1 m depth in geoclimatically different environments. Other objectives relating to implications for GHG emissions from livestock in pasture-tree vs.
Ian McIvor (15396875)   +4 more
core  

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

open access: yesAdvanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu   +10 more
wiley   +1 more source

Spatial patterns of cattle densities across the Brazilian Amazon revealed by very high-resolution satellite imagery. [PDF]

open access: yesCommun Sustain
Hodel L   +5 more
europepmc   +1 more source

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