In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen +5 more
wiley +1 more source
Microbiome Responses of Beef Steers to Rotational Grazing of Toxic Endophyte-Infected Tall Fescue Under Fall Conditions. [PDF]
Llada IM +8 more
europepmc +1 more source
A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance
Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng +12 more
wiley +1 more source
Research note: A longitudinal evaluation of feather corticosterone in two broiler genotypes in a pasture-based system. [PDF]
Aderibigbe AS.
europepmc +1 more source
HfO2‐based ferroelectrics exhibit wake‐up and fatigue behaviors during electrical cycling, significantly affecting device endurance and reliability. These phenomena are governed by defect dynamics, including oxygen vacancy redistribution and charge trapping.
Hongseok Kim +6 more
wiley +1 more source
Spatial patterns of cattle densities across the Brazilian Amazon revealed by very high-resolution satellite imagery. [PDF]
Hodel L +5 more
europepmc +1 more source
Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module
Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang +6 more
wiley +1 more source
Enteric methane emissions and mitigation strategies within pasture-based dairy systems. [PDF]
Kay J +6 more
europepmc +1 more source
Endothelin receptor type A (EDNRA) and the Hippo/YAP pathway form a self‐reinforcing loop that sustains triple‐negative breast cancer. EDNRA activates YAP through Gαq/11–Rho/ROCK–LATS signaling, while YAP/TEAD4 reciprocally drives EDNRA transcription.
Zehao Hong +10 more
wiley +1 more source
In Vitro Rumen Fermentation of Alternative Feeds Relevant for Dairy Production in an Overgrazed Tropical Area. [PDF]
Tadele F +4 more
europepmc +1 more source

