Results 21 to 30 of about 150,792 (295)

Plexiform Neurofibroma of the Wrist: Imaging Features and When to Suspect Malignancy

open access: yesCase Reports in Radiology, 2013
Plexiform neurofibromas are essentially pathognomonic for neurofibromatosis type 1 (NF1), occurring when there is diffuse involvement along a nerve segment and its branches.
Maria Gosein   +3 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Trends in extreme rainfall over the past 55 years suggest springtime subhourly rainfall extremes have intensified in Mahantango Creek, Pennsylvania

open access: yesScientific Reports
Extreme short-duration rainfall is intensifying with climate warming, and growing evidence suggests that subhourly rainfall extremes are increasing faster than more widely studied durations at hourly and daily timescales.
Anthony R. Buda   +4 more
doaj   +1 more source

Impact of P fertilizer and arbuscular mycorrhizal fungi on forage legume growth, chlorophyll content and productivity [PDF]

open access: yesPeerJ
Soil phosphorous (P) is the most limiting plant nutrient globally, reducing forage plant productivity. Although inorganic P fertilizers are used, about 75–90% of P becomes unavailable for plant uptake, hence, the strategies to enhance P uptake ...
Sanele Mpongwana   +5 more
doaj   +2 more sources

What is hindering the adoption of new annual pasture legumes?: Extension requirements to overcome these barriers [PDF]

open access: yes, 2009
Farmers and consultants were surveyed to identify current level of adoption and constraints to adoption of new annual pasture legumes in the mixed farming zone of Western Australia.
Hogg, N., Davis, J.K.
core  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Effect of Bambara nut and cowpea intercropped with maize at different times on nutritive quality of maize for ruminant feeding [PDF]

open access: yesMalaysian Journal of Animal Science, 2017
Effects of Bambara nut and cowpea planted with maize at different times on nutritive quality of maize forage were investigated. The study was laid out in a Completely Randomized Design and the treatments were combination of crop types (Bambara nut-maize (
Olanite, J. A.   +7 more
doaj  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Dietary Dried Jujube Fruit Powder (DJFP) Supplementation Improves Growth Performance, Antioxidant Stability, and Meat Composition in Broilers

open access: yesFoods, 2023
Nowadays, broiler production is faced with great challenges due to intensive culture modes, and chickens are more susceptible to oxidative stress.
Chao Yang   +7 more
doaj   +1 more source

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