Distribution of Big Tau Isoforms in the Human Central and Peripheral Nervous System
Objective Tau is widely studied in neurodegeneration, yet most work has focused on canonical brain tau isoforms. A longer isoform, “big tau,” produced by inclusion of exon 4a, is expressed in the peripheral nervous system (PNS) and central nervous system (CNS) regions.
Rama Krishna Koppisetti +17 more
wiley +1 more source
Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt +4 more
wiley +1 more source
Livestock Slurry and Sustainable Pasture Management: Microbial Roles, Environmental Impacts, and Regulatory Perspectives in Ireland and Europe. [PDF]
Silva MJ +6 more
europepmc +1 more source
Abstract Premise Applied ecology can significantly influence policy decisions on environmental issues. Therefore, research in this field should be as transparent and reproducible as possible. Existing expertise from a broad range of disciplines should also be integrated into ecological research to allow researchers to maximize understanding of complex ...
Kailin Weitkämper +5 more
wiley +1 more source
Changes in hematological and hematochemical parameters in lactating dairy sheep according to different pasture management and heat stress risk: A longitudinal study. [PDF]
Turini L +10 more
europepmc +1 more source
Abstract A recent debate has emerged between Caspar et al. (2024) and Herculano‐Houzel (2023) on inferring extinct dinosaur cognition by estimating brain neuron counts. While thought‐provoking, the discussion largely overlooks the function of cognition, as well as partly neglects the difficulties involved in estimating neuron numbers, which according ...
Thomas Rejsenhus Jensen +7 more
wiley +1 more source
Intensive pasture management alters the composition and structure of plant-pollinator interactions in Sibiu, Romania. [PDF]
Neacă AM, Meis J, Knight T, Rakosy D.
europepmc +1 more source
The 9+ month marathon: How pregnancy may have shaped human endurance capacities
Abstract Anthropology has long considered the evolution of our uniquely human endurance capacities to be the result of selection upon anatomical and physiological features imposed by the demands of thermoregulation and resource acquisition, particularly during the demands of persistence hunting. Research has focused on the anatomical changes present in
Cara Ocobock
wiley +1 more source
The pelvis doesn't walk by itself: Wider pelves reduce the cost of walking over unstable surfaces
Abstract Walking over variable and/or unstable terrain is a key aspect of daily life and was crucial to the evolution of bipedalism. The ability to find gait solutions that maintained stability over uneven terrain for the least increase in metabolic cost was likely a hallmark of locomotor effectiveness in early humans, in particular acting as an ...
Cara Wall‐Scheffler +2 more
wiley +1 more source

