Results 91 to 100 of about 1,083,264 (224)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Oral field cancerization: an update on current concepts
Oncology Reviews, 2014 There always exists a field with genetically altered cells with a high risk of developing premalignant and malignant lesions. It may often happen that an individual stem cell is genetically altered and can cause the formation of a clone or a patch which ...
Meenakshi Mohan, Nithya Jagannathan
doaj +1 more source
Reduction of particulate carryover from a pressurized fluidized bed [PDF]
A bench scale fluidized bed combustor was constructed with a conical shape so that the enlarged upper part of the combustor would also serve as a granular bed filter. The combustor was fed coal and limestone.
Patch, R. W.
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Regularity of the velocity field for Euler vortex patch evolution
, 2015 We consider the vortex patch problem for both the 2-D and 3-D incompressible Euler equations. In 2-D, we prove that for vortex patches with $H^{k-0.5}$ Sobolev-class contour regularity, $k \ge 4$, the velocity field on both sides of the vortex patch ...
Coutand, Daniel, Shkoller, Steve
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Ion temperatures in HIP-1 and SUMMA from charge-exchange neutral optical emission spectra [PDF]
Ion temperatures were obtained from observations of the H sub alpha, D sub alpha, and He 587.6 nm lines emitted from hydrogen, deuterium, and helium plasmas in the SUMMA and HIP-1 mirror devices at Lewis Research Center.
Lauver, M. R., Patch, R. W.
core +1 more source
Non-Gaussian sampling effects on the CMB power spectrum estimation
, 1997 We introduce a non-Gaussian model of structure formation, and show how it produces surprising sampling effects on the estimation of the CMB power spectrum. Estimates of the average power spectrum based on small sky patches produce qualitatively different
Cheung, Charlotte, Magueijo, Joao
core +1 more source