Results 121 to 130 of about 1,521,241 (378)

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Regularity of the velocity field for Euler vortex patch evolution

open access: yes, 2015
We consider the vortex patch problem for both the 2-D and 3-D incompressible Euler equations. In 2-D, we prove that for vortex patches with $H^{k-0.5}$ Sobolev-class contour regularity, $k \ge 4$, the velocity field on both sides of the vortex patch ...
Coutand, Daniel, Shkoller, Steve
core  

High order continuous polygonal patches [PDF]

open access: yes, 1991
A polygonal patch method is described which can be used to fill a polygonal hole within a given k'th order continuous rectangular patch complex. The method is relatively easy to implement, since it only re- quires Ck extensions of the rectangular patch ...
Gregory, JA, Hahn, JM, Lau, VKH
core  

Microneedle patch for the ultrasensitive quantification of protein biomarkers in interstitial fluid

open access: yesNature Biomedical Engineering, 2021
Zheyu Wang   +16 more
semanticscholar   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

Foraging as an evidence accumulation process

open access: yes, 2018
A canonical foraging task is the patch-leaving problem, in which a forager must decide to leave a current resource in search for another. Theoretical work has derived optimal strategies for when to leave a patch, and experiments have tested for ...
Davidson, Jacob D., Hady, Ahmed El
core   +1 more source

Real-Time Healthcare Data Transmission for Remote Patient Monitoring in Patch-Based Hybrid OCC/BLE Networks

open access: yesSensors, 2019
Research on electronic healthcare (eHealth) systems has increased dramatically in recent years. eHealth represents a significant example of the application of the Internet of Things (IoT), characterized by its cost effectiveness, increased reliability ...
Moh. Khalid Hasan   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy