Results 221 to 230 of about 1,187,119 (348)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Shagreen Patch in Tuberous Sclerosis Complex at High-Frequency Ultrasound. [PDF]

Diagnostics (Basel)
Tagliati C, Wortsman X.
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Laser-programmed stiffness and interfaces for textile hybrid electronics. [PDF]

Nat Commun
Luo H, Cai Z, Yang G, Ye K, Tang J, Liu T, He L, Zhang Y, Zhu Y, Xie H, Nan K, Yang H, Dickey MD, Xu K.   +13 more
europepmc   +1 more source

Deep Patch Visual SLAM [PDF]

Lahav Lipson, Zachary Teed, Jia Deng
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Hierarchical habitat selection by a predatory fish in a patchy seascape. [PDF]

Sci Rep
Rodemann J, White M, James WR, Griffin LP, Costa SV, Furman BT, Pittman SJ, Gann D, Rehage JS, Santos RO.   +9 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Patch [PDF]

, 2020
openaire   +3 more sources

Dinner Date: Opposite-Sex Pairs of Fruit Bats (<i>Rousettus aegyptiacus</i>) Forage More than Same-Sex Pairs. [PDF]

Biology (Basel)
Pergams A, Haus M, Estrada C, Brown J, Salles A.   +4 more
europepmc   +1 more source