Results 91 to 100 of about 16,362,977 (342)
Dense U-net Based on Patch-Based Learning for Retinal Vessel Segmentation
Entropy, 2019 Various retinal vessel segmentation methods based on convolutional neural networks were proposed recently, and Dense U-net as a new semantic segmentation network was successfully applied to scene segmentation.
Chang Wang +4 more
semanticscholar +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Testing Holographic Conjectures of Complexity with Born-Infeld Black Holes
, 2017 In this paper, we use Born-Infeld black holes to test two recent holographic conjectures of complexity, the "Complexity = Action" (CA) duality and "Complexity = Volume 2.0" (CV) duality. The complexity of a boundary state is identified with the action of
Tao, Jun, Wang, Peng, Yang, Haitang
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A segmentation-free isogeometric extended mortar contact method
, 2018 This paper presents a new isogeometric mortar contact formulation based on an extended finite element interpolation to capture physical pressure discontinuities at the contact boundary. The so called two-half-pass algorithm is employed, which leads to an
De Lorenzis, Laura +2 more
core +1 more source
Clinical, Cosmetic and Investigational Dermatology, 2023 Chidubem AV Okeke,1 Ramona Khanna,2 Alison Ehrlich3 1Department of Dermatology, Howard University College of Medicine, Washington, DC, USA; 2Georgetown University School of Medicine, Washington, DC, USA; 3Foxhall Dermatology, Washington, DC ...
Okeke CAV, Khanna R, Ehrlich A
doaj
Systemic contact dermatitis due to nickel
JDVI (Journal of General Procedural Dermatology & Venereology Indonesia), 2015 Introduction: Systemic contact dermatitis (SCD) is a systemic reactivation of a previous allergic contact dermatitis. The initial exposure may usually be topical, followed by oral, intravenous or inhalation exposure leading to a systemic hypersensitivity
Taruli Olivia +2 more
doaj +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Fixed Food Eruption Caused by Cashew Nut
Allergology International, 2008 Background: The diagnosis of fixed ‘drug’ eruption is not difficult for dermatologists, but it is difficult to identify the causative agent when the patient denies ingestion of any drugs. There have been some reported cases of fixed ‘food’ eruption. Case
Satoshi Fukushima +2 more
doaj +1 more source