Results 251 to 260 of about 14,397,534 (393)

Correction: Patch test results in paediatric patients with atopic dermatitis in Laos. [PDF]

open access: yesPLoS One, 2020
Wootton CI   +4 more
europepmc   +1 more source

Testing the Generality of Patch and Landscape-Level Predictors of Tree Squirrel Occurrence at a Regional Scale [PDF]

open access: bronze, 2007
Robert K. Swihart   +3 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

IgE to wheat, prick test, and Patch test among children with celiac disease. [PDF]

open access: yesBMC Pediatr
Khalighi M   +5 more
europepmc   +1 more source

Patch testing in children, adults and elderly: Influence of age and sex on sensitization patterns

open access: bronze, 2002
Stefan Wöhrl   +4 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Use of human predictive patch test (HPPT) data for the classification of skin sensitization hazard and potency. [PDF]

open access: yesArch Toxicol
Herzler M   +13 more
europepmc   +1 more source

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