Results 261 to 270 of about 14,199,958 (398)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Validation of pencil beam scanning proton therapy with multi‐leaf collimator calculated by a commercial Monte Carlo dose engine

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract This study aimed to evaluate the clinical beam commissioning results and lateral penumbra characteristics of our new pencil beam scanning (PBS) proton therapy using a multi‐leaf collimator (MLC) calculated by use of a commercial Monte Carlo dose engine.
Yuki Tominaga, Yusuke Sakurai, Junya Miyata, Shuichi Harada, Takashi Akagi, Masataka Oita   +5 more
wiley   +1 more source

IgE to wheat, prick test, and Patch test among children with celiac disease. [PDF]

BMC Pediatr
Khalighi M, Javaherizadeh H, Hakimzadeh M, Ahmadi M, Torabizadeh M, Fayezi A.   +5 more
europepmc   +1 more source

Clinical manifestations and patch test results for facial dermatitis associated with disposable face mask use during the COVID-19 outbreak: A case-control study. [PDF]

J Am Acad Dermatol, 2021
Kang SY, Chung BY, Kim JC, Park CW, Kim HO.   +4 more
europepmc   +1 more source

European Society of Contact Dermatitis guideline for diagnostic patch testing – recommendations on best practice

Contact Dermatitis, 2015
J. Johansen, K. Aalto-Korte, T. Agner, K. Andersen, A. Bircher, M. Bruze, A. Cannavó, A. Giménez-Arnau, M. Gonçalo, A. Goossens, S. John, C. Lidén, M. Lindberg, V. Mahler, M. Matura, T. Rustemeyer, J. Serup, R. Spiewak, J. P. Thyssen, M. Vigan, I. White, M. Wilkinson, W. Uter   +22 more
semanticscholar   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source

Effect of different noise reduction techniques and template matching parameters on markerless tumor tracking using dual‐energy imaging

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To evaluate the impact of various noise reduction algorithms and template matching parameters on the accuracy of markerless tumor tracking (MTT) using dual‐energy (DE) imaging. Methods A Varian TrueBeam linear accelerator was used to acquire a series of alternating 60 and 120 kVp images (over a 180° arc) using fast kV switching, on ...
Mandeep Kaur, Peter Wagstaff, Hassan Mostafavi, Mathias Lehmann, Daniel Morf, Liangjia Zhu, Hyejoo Kang, Michal Walczak, Matthew M. Harkenrider, John C. Roeske   +9 more
wiley   +1 more source

Use of human predictive patch test (HPPT) data for the classification of skin sensitization hazard and potency. [PDF]

Arch Toxicol
Herzler M, Abedini J, Allen DG, Germolec D, Gordon J, Ko HS, Matheson J, Reinke E, Strickland J, Thierse HJ, To K, Truax J, Vanselow JT, Kleinstreuer N.   +13 more
europepmc   +1 more source

Correction: Patch test results in paediatric patients with atopic dermatitis in Laos. [PDF]

PLoS One, 2020
Wootton CI, Sodaly MK, Billamay SX, English JSC, Mayxay M.   +4 more
europepmc   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source