Results 81 to 90 of about 16,362,977 (342)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Trichloroethylene Hypersensitivity Syndrome Is Potentially Mediated through Its Metabolite Chloral Hydrate. [PDF]

open access: yesPLoS ONE, 2015
We documented previously the entity of trichloroethylene (TCE) hypersensitivity syndrome (THS) in occupational workers.To identify the culprit causative compound, determine the type of hypersensitivity of THS, and establish a screening test for subjects ...
Yongshun Huang   +7 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A patch that imparts unconditional stability to certain explicit integrators for SDEs [PDF]

open access: yes, 2010
This paper proposes a simple strategy to simulate stochastic differential equations (SDE) arising in constant temperature molecular dynamics. The main idea is to patch an explicit integrator with Metropolis accept or reject steps.
Bou-Rabee, Nawaf, Vanden-Eijnden, Eric
core  

Clinical Relevance of Contact Allergy to Gold Sodium Thiosulphate in Fibromyalgia

open access: yesActa Dermato-Venereologica
Fibromyalgia is a chronic syndrome characterized by pain, fatigue, and cognitive disturbances. The increased prevalence of contact allergy to gold in individuals with fibromyalgia when compared with the general population has previously been described ...
Katharine Hopkins   +7 more
doaj   +1 more source

Comparison of pavement surface texture determination by sand patch test and 3D laser scanning

open access: yes, 2012
A modern highway must be capable of proving traffic safety, comfort to passengers as well as efficient and economical transportation. In view of the increase in the number of traffic accidents due to the developments in automotive industry, the traffic ...
B. Sengoz, A. Topal, Serhan Tanyel
semanticscholar   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Searching the Sky with CONFIGR-STARS [PDF]

open access: yes, 2009
SyNAPSE program of the Defense Advanced Projects Research Agency (HRL Laboratories LLC, subcontract #801881-BS under DARPA prime contract HR0011-09-C-0001); CELEST, a National Science Foundation Science of Learning Center (SBE-0354378)CONFIGR-STARS, a ...
Carpenter, Gail A., Ravindran, Arun K.
core   +1 more source

Complexity growth rates for AdS black holes in massive gravity and $f(R)$ gravity

open access: yes, 2017
The "complexity = action" duality states that the quantum complexity is equal to the action of the stationary AdS black holes within the Wheeler-DeWitt patch at late time approximation.
Guo, Wen-Di   +3 more
core   +1 more source

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