Results 51 to 60 of about 3,155,738 (288)

Acute generalized exanthematous pustulosis induced by ceftriaxone with positive patch testing

Acute generalized exanthematous pustulosis (AGEP) is a rare severe cutaneous reaction. In over 90% of patients it is an adverse reaction to drugs. Delayed-type (type IV) hypersensitivity seems to play an important role in its pathophysiology.
Carmem Botelho, Lise Brosseron, Ana Gabriela Lopes   +2 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Atopic patch testing

Indian Journal of Dermatology, Venereology and Leprology, 2008
Atopic dermatitis is a major problem among the urban population and it can be aggravated or triggered by various allergens. Atopic patch test can be used as a diagnostic tool in characterizing patients with allergen triggered atopic dermatitis.1. Patch testing to reproduce an eczematous reaction by applying prick test allergens under occlusion on ...
Krupa, Shankar DS, Chakravarthi, M
openaire   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Soft Sensing of Local Skin Reactions: A Computer Vision Approach Using Deep Model Colour Space Analysis for Objective Patch Test Evaluation

Sensors
Allergic contact dermatitis (ACD) is a prevalent condition traditionally diagnosed using standardized patch testing, a method limited by subjective visual skin evaluation and delayed skin reaction manifestations.
Dominyka Stragyte, Vaiva Paskeviciute, Vidas Raudonis, Kestutis Stasaitis, Skaidra Valiukeviciene   +4 more
doaj   +1 more source

Patch testing in Lao medical students.

PLoS ONE, 2020
BACKGROUND:Dermatological services in Laos, South East Asia are limited to the capital and patch testing is currently not available, so no data exists regarding the common cutaneous allergens in this population.
Catriona I Wootton, Mick Soukavong, Sonexai Kidoikhammouan, Bounthome Samountry, John S C English, Mayfong Mayxay   +5 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Evidence-based diagnosis in patch testing

, 2003
Evidence-based medicine (EBM) is defined as the integration of the best research evidence with clinical expertise and patient values. Based on the principles of EBM, we can conclude that patch testing is cost-effective only if patients are selected on ...
van der Valk, PGM, Coenraads, PJ, Devos, SA   +2 more
core   +2 more sources

Patch Testing in Non-Immediate Drug Eruptions

Allergy, Asthma & Clinical Immunology, 2008
The present review addresses the literature regarding the sensitivity and specificity of the various diagnostic methods for evaluating non-immediate (ie, occurring more than 1 hour after drug administration) hypersensitivity reactions associated with β ...
Romano Antonino, Viola Marinella, Gaeta Francesco, Rumi Gabriele, Maggioletti Michela   +4 more
doaj   +1 more source