Results 231 to 240 of about 14,137,188 (298)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Allergic Contact Dermatitis to Terminalia Chebula Fruit Extract in Antiaging Creams. [PDF]

Contact Dermatitis
Blanchard M, Marchal O, Blanchard G, Piletta-Zanin P.   +3 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

IL-9 and IL-24 biomarkers in the transcriptional signature of contact dermatitis to methylisothiazolinone. [PDF]

Front Immunol
de Melo TC, Sotto MN, Fernandes IG, De Sousa ESA, Ferreira FM, Simões GB, Ramos YÁL, Pincelli MS, Dos Reis VMS, Sato MN.   +9 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

An Anisotropic and Stable-Conductance Patch for Mechanical-Electrical Coupling With Infarcted Myocardium. [PDF]

Exploration (Beijing)
Li Y, Miao Y, Wei L, Li W, Shan M, Jiang Q, Wang F, Wang L, Zhang Z, Song J, Zhu Y, Mao J.   +11 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Exogenous estradiol modulates entorhinal cortex contributions to episodic encoding of conditioned threat in women. [PDF]

Psychoneuroendocrinology
Oliver KI, Dahlgren K, Roeckner AR, Hinojosa CA, Santos JLC, Taylor LS, Zeleke H, Murphy A, Johnson C, DelRosario D, Ely TD, Hinrichs R, Merrill NA, Young MR, Braden A, Powers A, Rooij SJHV, Michopoulos V, Stevens JS.   +18 more
europepmc   +1 more source

Reduction in chromium sensitization: a retrospective analysis from 2010 to 2024 in a dermatology allergy service. [PDF]

An Bras Dermatol
Hafner MFS, Duarte IAG, Souza BCM, Lazzarini R.   +3 more
europepmc   +1 more source

An infant with drug reaction with eosinophilia and systemic symptoms caused by phenobarbital and amoxicillin: A case report. [PDF]

Medicine (Baltimore)
Matsumoto Y, Fujita M, Inuo C, Inuo C.
europepmc   +1 more source