Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang +6 more
wiley +1 more source
Experimental Study on the Bending Behaviour of GFRP Laminates Repaired with Stainless-Steel Wire Mesh. [PDF]
Taş H, Ünal HY.
europepmc +1 more source
Atopy Patch Test – Reproducibility and Elicitation of Itch in Different Application Sites
Stephanie Weissenbacher +5 more
openalex +1 more source
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda +9 more
wiley +1 more source
An infant with drug reaction with eosinophilia and systemic symptoms caused by phenobarbital and amoxicillin: A case report. [PDF]
Matsumoto Y, Fujita M, Inuo C.
europepmc +1 more source
Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno +12 more
wiley +1 more source
Evidential deep learning-based ALK-expression screening using H&E-stained histopathological images. [PDF]
Kosaraju SC +7 more
europepmc +1 more source
Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu +12 more
wiley +1 more source
Epidemiological profile and main allergens identified in cases of allergic contact cheilitis. [PDF]
Souza BCM +3 more
europepmc +1 more source
U.S. Law of the Sea Cruise to Map the Eastern Mendocino Ridge, Eastern Pacific Ocean [PDF]
Gardner, James V., Malik, Mashkoor A.
core +2 more sources

