Results 241 to 250 of about 14,105,689 (382)

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Results of Patch Testing With a Brazilian Propolis Dilution Series. [PDF]

Contact Dermatitis
van Oers EM, Ipenburg NA, de Groot AC, Rustemeyer T.   +3 more
europepmc   +1 more source

Skin Tests of a Novel Nicotine Patch, PHK-301p, in Healthy Male Volunteers: Phase I, Placebo-Controlled Study

, 2006
Shin Irie, Hiroshi Tsukikawa, Toshitaka Nabeshima, Makiko Usami, Tadaaki Karino, Shuichi Komatsu, Moriaki Akasaki   +6 more
openalex   +2 more sources

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Magnetic nanostickers for active control of interface-enhanced selective bioadhesion. [PDF]

Nat Commun
Hou C, Guo J, Sun B, Chan KF, Song X, Zhang L.   +5 more
europepmc   +1 more source

Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K

FEBS Open Bio, EarlyView.
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley   +1 more source

<i>Accept-reject</i> decision-making revealed via a quantitative and ethological study of <i>C. elegans</i> foraging. [PDF]

Elife
Haley JA, Chen T, Aoi M, Chalasani SH.
europepmc   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

Evaluating the Efficacy of Soothing Agents in Mitigating 0.1% Retinol-Induced Skin Irritation: A Patch Test. [PDF]

J Cosmet Dermatol
Ying Y, Fang Y, Chenlan X, Lin S, Jiefang H, Yanan L, Peiwen S.   +6 more
europepmc   +1 more source

A Case Report of a Metal Allergy Patient Whose Prosthesis was Identified Allergenic by Non-destructive Metal Element Analysis and a Dermatological Patch Test

, 2006
Atsushi Mine
openalex   +2 more sources