FEBS Open Bio, EarlyView.Sarcosine oxidase from Bacillus sp. (SoxB) recognizes l‐proline (l‐Pro), d‐proline (d‐Pro), and l‐thioproline (l‐Tpr) as minor substrates. In this study, we measured their absorption spectra, determined the crystal structures of their enzyme complexes, and performed site‐directed mutagenesis of key residues.
Yuqi Zhang +5 more
wiley +1 more source
Behavior of Defective Aluminum Panels Under Shear Forces Patched with Composite Plates-A New Engineering Approach. [PDF]
Materials (Basel)Simanovskii Y, Abramovich H.
europepmc +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Evaluating Pain Response and Clinical Efficacy of an Articaine Mucoadhesive Patch among 6-12-year-old Children during Local Anesthetic Injection and Subgingival Tooth Preparation: A Double-blind Nonrandomized Clinical Trial. [PDF]
Int J Clin Pediatr DentDhote S +5 more
europepmc +1 more source
Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations
FEBS Open Bio, EarlyView.Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro +8 more
wiley +1 more source
Prevalence of reactive allergens in contact patch testing studies using the Brazilian standard battery: a systematic review. [PDF]
An Bras DermatolBueno ALA, Aguzzoli NHG, Bonamigo RR.
europepmc +1 more source
FEBS Open Bio, EarlyView.Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
Caprylhydroxamic Acid: A Growing Allergen in Skincare Products. [PDF]
Contact DermatitisTheret V, Burle E, Giordano F.
europepmc +1 more source
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
A survey of critically endangered plecturocebus oenanthe in moyobamba's urban forests, Peru. [PDF]
Sci RepShanee S +7 more
europepmc +1 more source