Results 41 to 50 of about 848,646 (270)

Safety of opioid patch initiation in Australian residential aged care [PDF]

open access: yes, 2015
Explores opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Abstract Objective: To explore opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Design:
Elizabeth Roughead   +2 more
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Estradiol matrix patches for pubertal induction: stability of cut pieces at different temperatures

open access: yesEndocrine Connections, 2019
Objective: Transdermal estradiol patches are primarily designed for adult women. No low-dose patches are licensed for pubertal induction in hypogonadal girls. Low doses can be achieved by cutting a matrix patch into smaller pieces.
Carina Ankarberg-Lindgren   +5 more
doaj   +1 more source

Identifying Patch Correctness in Test-Based Program Repair

open access: yes, 2018
Test-based automatic program repair has attracted a lot of attention in recent years. However, the test suites in practice are often too weak to guarantee correctness and existing approaches often generate a large number of incorrect patches. To reduce
Huang, Gang   +4 more
core   +1 more source

A systematic approach to the formulation of anti-onychomycotic nail patches [PDF]

open access: yes, 2018
Nail patches have a potential role as drug carriers for the topical treatment of nail diseases such as onychomycosis, a common condition. O ur aim was therefore to develop a systematic and novel appr oach to the formulat ion of a simple drug -in-adhesive
Charalambides, MN   +5 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Ethnic-Cultural Identity and Dating of the Clothing Clasp Group from the Territory of Prut-Dniester Interfl uve

open access: yesПоволжская археология, 2017
The article considers a group of non-ferrous metal patches discovered in the territory of the Pruto-Dniester region. An analysis of several analogies allowed the authors to conclude that these items represent paired clothing clasps.
Riabtseva Svetlana S.   +1 more
doaj   +1 more source

Geometric phases for corotating elliptical vortex patches [PDF]

open access: yes, 2000
We describe a geometric phase that arises when two elliptical vortex patches corotate. Using the Hamiltonian moment model of Melander, Zabusky, and Styczek [J. Fluid Mech. 167, 95–115 (1986)] we consider two corotating uniform elliptical patches evolving
Newton, P. K., Shashikanth, B. N.
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Identification of bald patches in degraded alpine meadows by UAV-based remote sensing and deep learning

open access: yesAll Life
Alpine meadow patchiness is the starting point and an important feature of the formation of ‘Black Beach’ on the Tibetan Plateau, which directly threatens regional ecological security and economic development. Therefore, exploring an efficient, rapid and
Lu Wang   +5 more
doaj   +1 more source

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