Results 31 to 40 of about 7,228 (204)

In Situ Profiling of Nanoscale Strains Uncovers Mechano‐Architectural Predictors of Aging and Osteoarthritis Emergence

Advanced Science, EarlyView.
In situ mechanical loading of osteoarthritis‐prone murine knee joints reveals that spatial alterations in subchondral plate microarchitecture precede cartilage loss and promote a shift from coordinated epiphyseal strain dissipation in healthy joints to focal subchondral strain concentration in osteoarthritis‐prone joints.
Aikta Sharma, Lucinda A. E. Evans, Lucie E. Bourne, Jishizhan Chen, Alissa L. Parmenter, Joseph Brunet, Kamel Madi, Sebastian Marussi, Andrew A. Pitsillides, Peter D. Lee, Katherine A. Staines   +10 more
wiley   +1 more source

Effect of Patellar Morphology on the Risk of Osteochondral Fracture after Patellar Dislocation: A Cross‐sectional Study

Orthopaedic Surgery
Objective The risk of osteochondral fracture (OCF) after patellar dislocation has been shown to be related to patellofemoral anatomy, but its relationship to patellar morphology remains unknown.
Zirui Zhou, Qiang Hua, Chenghong Wen, Wenduo Qian, Jide Su, Min Yang, Mingming Lei   +6 more
doaj   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Tibial Tubercle to Trochlear Groove Distance and Index in Children with One-Time versus Recurrent Patellar Dislocation: A Magnetic Resonance Imaging Study

Journal of Orthopaedic Surgery, 2016
Purpose To compare the tibial tubercle to trochlear groove (TT-TG) distance and index using magnetic resonance imaging (MRI) between children with one-time and recurrent patellar dislocation. Methods Records of first-time acute patellar dislocations from
Ching Sing Nicholas Yeoh, Kai Yet Lam
doaj   +1 more source

Clinical Outcomes After Medial Patellofemoral Ligament Reconstruction With Suture Fixation of the Gracilis Tendon via Transosseous Tunnels

Orthopaedic Journal of Sports Medicine, 2020
Background: Several fixation methods have been introduced in medial patellofemoral ligament (MPFL) reconstruction. However, the optimal management of patients with recurrent patellar dislocation remains controversial.
Hangzhou Zhang, Mao Ye MD, Qingwei Liang MD   +2 more
doaj   +1 more source

Early results of surgically treated patellar osteochondral fracture following patellar dislocation in adolescents [PDF]

The Egyptian Orthopaedic Journal, 2019
BackgroundAdolescents having knee ligaments laxity are more predisposed to patellar dislocation. Associated patellar osteochondral fractures (OCFs) denote a main complication. Many surgical options have been described to treat such injury.
Osama Gamal, Ahmed Shams
doaj   +1 more source

Musculoskeletal Phenotypes of 19 Patients With X‐Linked HNRNPH2‐Related Neurodevelopmental Disorder: A Prospective Case Series

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Detailed clinical phenotypes have been previously reported for 33 individuals with X‐linked HNRNPH2‐related neurodevelopmental disorder. Of these, 75% self‐reported a musculoskeletal abnormality, including hip dysplasia, scoliosis, kyphosis, lordosis, pes planus, arthritis, and missing spinous processes.
Ambar Garcia, Rachel Salazar, Nicole Holuba, Franklin E. Paulino, Michael G. Vitale, Jennifer M. Bain, Joshua Hyman   +6 more
wiley   +1 more source

Missed Transient Patellar Dislocation in Younger Patients With Traumatic Knee Injuries

Journal of Orthopedic and Spine Trauma, 2016
Background: Acute patellar dislocation is a common injury, with up to 40% of the cases missed due to a high rate of spontaneous reduction. Complications mainly arise due to osteochondral fractures, resulting in patellofemoral osteoarthritis and rupture ...
Soroush Baghdadi, SM Javad Mortazavi, Mohammad Hassan Kaseb, Mohammad Ayati   +3 more
doaj   +1 more source

Adipose‐derived mesenchymal stem cell injection into the KI10 acupoint mitigates cartilage damage in KOA rats through PGE2‐mediated α7nAChR/NF‐κB pathway

Animal Models and Experimental Medicine, EarlyView.
In our research, KOA rat models were established and treated with ADSC injection into the KI10 acupoint. Pain relief, behavioral function, and joint structural improvements were systematically assessed using ethological tests, imaging, histopathological staining, transmission electron microscopy, and molecular analyses.
Mengwei Dong, Wenfang Li, Wanpeng Yang, Te Ba, Nan Nan, Yang Liu, Jing Han, Huiqin Hao   +7 more
wiley   +1 more source

The morphology of patella changed significantly after soft tissue correction for children with recurrent patella dislocation

BMC Musculoskeletal Disorders, 2020
Background Although morphological improvement of femoral trochlea has been investigated in children with patellar dislocation after surgery, whether the patellar shape changed under the same condition is still unknown.
Jinghui Niu, Qi Qi, Kuo Hao, Wei Lin, Kang Piao, Fei Wang   +5 more
doaj   +1 more source