Results 241 to 250 of about 224,775 (387)

Aberrant Gait Biomechanics Linked to Cartilage Changes After ACL Reconstruction in Those With High Body Mass Index

open access: yesJournal of Orthopaedic Research, Volume 43, Issue 8, Page 1413-1422, August 2025.
ABSTRACT A history of anterior cruciate ligament reconstruction (ACLR) and high body mass index (BMI) are strong risk factors for incident knee osteoarthritis. Limited research has evaluated the interaction between ACLR and high BMI on limb‐level loading and early deleterious changes in cartilage health.
Hyunwook Lee   +10 more
wiley   +1 more source

Acute Prolonged Hamstrings Vibration Reduces Limb Stiffness Following Anterior Cruciate Ligament Reconstruction During a Single‐Limb Drop‐Jump Task

open access: yesJournal of Orthopaedic Research, Volume 43, Issue 8, Page 1442-1453, August 2025.
ABSTRACT Impaired quadriceps function influences lower limb biomechanics following anterior cruciate ligament reconstruction (ACLR). This often results in stiff limb loading which leads to the development of knee osteoarthritis. Greater hamstrings/quadriceps co‐activation is common after ACLR and is, in part, responsible for impaired quadriceps ...
Timothy Lowe   +3 more
wiley   +1 more source

Amelogenin Null Mice Develop Osteoarthritis, While Its Application Mitigates Disease Phenotypes in a Rat Model

open access: yesThe FASEB Journal, Volume 39, Issue 14, 31 July 2025.
Aged amelogenin‐null mice developed severe osteoarthritic features. In a rat model of induced osteoarthritis, a single application of a recombinant human amelogenin inhibited joint deterioration and induced partial healing, while increasing type II collagen and decreasing MMP‐13 and type X collagen, 24 weeks posttreatment.
Omer Helwa‐Shalom   +12 more
wiley   +1 more source

Physeal-Sparing MPFL Reconstruction Technique With Lateral Retinaculum Lengthening. [PDF]

open access: yesVideo J Sports Med
Qian LJ   +4 more
europepmc   +1 more source

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

open access: yesAdvanced Science, Volume 12, Issue 26, July 10, 2025.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang   +9 more
wiley   +1 more source

Optimal flexion angle for graft fixation in lateral extra‐articular tenodesis combined with anterior cruciate ligament reconstruction: A systematic review

open access: yesJournal of Experimental Orthopaedics, Volume 12, Issue 3, July 2025.
Abstract Purpose This systematic review aims to investigate the knee flexion angles used for graft fixation in lateral extra‐articular tenodesis (LET) during anterior cruciate ligament reconstruction (ACLR) and their impact on clinical outcomes. Methods Following PRISMA guidelines, MEDLINE/PubMed and EMBASE were searched up to February 2024.
Riccardo Compagnoni   +6 more
wiley   +1 more source

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