Results 41 to 50 of about 22,899 (293)

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source

Combined Medial Patellofemoral Ligament and Medial Quadriceps Tendon-Femoral Ligament Reconstruction With Single Knotless Anchor

Arthroscopy Techniques
Lateral patellar dislocations represent a common orthopaedic condition in young, active individuals who experience patellar instability. Despite increasing interest in re-creating the natural biomechanics and native knee anatomy when performing medial ...
Mathew Hargreaves, B.S., Hamp Sisson, B.S., Chandler Harris, B.S.E., Amit M. Momaya, M.D., Aaron J. Casp, M.D.   +4 more
doaj   +1 more source

Combined Reconstruction of the Medial Patellofemoral Ligament and Medial Quadriceps Tendon–Femoral Ligament

Arthroscopy Techniques, 2021
Most patellar dislocations are associated with disruption of the proximal medial patellar restraints (PMPRs). The PMPRs comprise the medial patellofemoral ligament (MPFL) and medial quadriceps tendon–femoral ligament (MQTFL).
Eduardo Frois Temponi, M.D., M.Sc., Adnan Saithna, M.D., F.R.C.S.(T&O), Matheus Braga Jacques Gonçalves, M.D., Luiz Fernando Machado Soares, M.D., M.Sc., Rafael Baroni Carvalho, M.D., Lúcio Honório de Carvalho Júnior, M.D., Ph.D.   +5 more
doaj   +1 more source

A Biomimetic Lubricant Captures Hyaluronic Acid In Situ to Regenerate Cartilage: From Bench to Bedside

Advanced Science, EarlyView.
(a) The outstanding lubricative properties of natural articular cartilage arise from a composite coating composed of HA, lubricin, and phospholipids at its surface. Notably, lubricin facilitates the enrichment of synovial HA onto cartilage surfaces, and HA complexes with phospholipids, a key component to maintain extremely low friction under high ...
Yongan Lin, Zijian Yan, Jiayi Chen, Xiaochao Wang, Ruibin Lin, Yunqi Fu, Zhaoying Lv, Bohui Wu, Xuewei Cao, Renjian Xie, Ming Dong, Chenxiao Zheng, Li Ren   +12 more
wiley   +1 more source

Medial Quadriceps Tendon Femoral Ligament Reconstruction Technique and Surgical Anatomy

Arthroscopy Techniques, 2019
Medial patellofemoral ligament reconstruction risks patellar fracture with the osseous violation necessary for patellar attachment. Anatomic studies identify an entire medial patellofemoral complex of structures responsible for medial restraint to ...
Sheeba M. Joseph, M.D., M.S., John P. Fulkerson, M.D.   +1 more
doaj   +1 more source

Mechanics of the patellar articulation Effects of patellar ligament length studied with a mathematical model [PDF]

Acta Orthopaedica Scandinavica, 1987
We investigated the influence of the length of the patellar ligament on (1) the relative positions of the ligament, patella, and quadriceps tendon, (2) the location of the patellofemoral contact point, (3) the force of the quadriceps femoris muscle, and (4) the patellofemoral compression force for 0-120 degrees flexion-extension angles of the knee. For
T M, van Eijden, E, Kouwenhoven, W A, Weijs   +2 more
openaire   +2 more sources

Anti‐inflammatory and osteogenic effects of transcutaneous electrical nerve stimulation in knee osteoarthritis rats via the regulation of the intestinal microbiota

Animal Models and Experimental Medicine, EarlyView.
Transcutaneous electrical nerve stimulation (TENS) improved knee osteoarthritis (KOA) in rats by regulating interleukin‐1β (IL‐1β), IL‐6, and IL‐8 expressions and the bone morphogenetic protein 2 (BMP‐2)/transforming growth factor β (TGF‐β) signaling pathway.
Yan Sun, Tong Ma, Ran Chen, Lan Shen, Xun Tang, Zhiqiang Shen, Hongbin Zhao   +6 more
wiley   +1 more source

Resistência mecânica do ligamento patelar após a retirada do terço médio com incisão longitudinal ou duas mini-incisões transversas Patellar ligament strength after removal of the middle-third through either one longitudinal incision or two mini-transverse incisions

Revista Brasileira de Ortopedia, 2010
OBJETIVO: Avaliar a resistência e a regeneração do ligamento patelar após a retirada de enxerto para reconstrução do ligamento cruzado anterior, utilizando a técnica tradicional de incisão na pele única longitudinal e uma técnica de duas mini-incisões ...
Leandro Calil De Lazari, Cleber Antonio Jansen Paccola   +1 more
doaj   +1 more source

Repair of Acute Patellar Tendon Rupture Using an Internal Brace Technique

Case Reports in Orthopedics, 2021
Acute patellar tendon rupture is a serious injury, resulting in the disruption of the knee extensor mechanism. Many authors recommend augmented repairs of patellar tendon ruptures to allow early active rehabilitation.
Aki Fukuda, Shigeto Nakazora, Akinobu Nishimura, Ko Kato   +3 more
doaj   +1 more source

Systemic Hormonal Contraceptive Use Is Associated With Greater Odds of Rotator Cuff Tears, Shoulder Instability, Dislocation, and Other Shoulder Pathologies: A Propensity Matched Epidemiological Study

Arthroscopy, EarlyView.
Purpose To evaluate whether systemic estrogen‐only, progestin‐only, or combined hormonal contraceptives (HCs) are associated with increased risk of shoulder pathologies in reproductive‐age females. Methods A retrospective cohort study of female patients presenting to clinic from 2013 to 2020 and aged 13‐50 with 5 years of follow‐up was conducted using ...
Argen Omurzakov, Arsen M. Omurzakov, Robert J. Burkhart, Aakash K. Shah, Rayyan Abid, James E. Voos, Jacob G. Calcei, John M. Apostolakos   +7 more
wiley   +1 more source