Results 91 to 100 of about 581,668 (293)

Patent trolls and patent-busters

, 2008
In recent times, there have been concerns that the patent system been abused by opportunistic companies known by the phrase "patent trolls". It has been alleged that such entities have stunted innovation and spurred unnecessary patent litigation..
Rimmer, Matthew
core  

Technology Adoption and Fuzzy Patent Rights [PDF]

, 2010
This paper considers why a patentee may have little incentives to reduce the uncertainty of patent boundary. Clearer patent rights, i.e., when patent examination results better predict subsequent court decisions, provide better guidance to ...
Chiou, Jing-Yuan
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Patent for Rat Trap

, 1922
Patent for Rat ...
Compton, John.T.
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Improving the Performance of a Korean Patent Document Search Model using KorPatBERT-based CPC Classification Model

Journal of Intellectual Property
The global competition for technological supremacy is intensifying, prompting every country to focus on securing technological advantages through patent acquisition.
Jaeok Min, Hansung Noh, Minhak Kwak, Solbin Hwang, Taehoon Kim   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Semantic Consistency and Correctness Verification of Digital Traffic Rules

Engineering
The consensus of the automotive industry and traffic management authorities is that autonomous vehicles must follow the same traffic laws as human drivers.
Lei Wan, Changjun Wang, Daxin Luo, Hang Liu, Sha Ma, Weichao Hu   +5 more
doaj   +1 more source

Engineer's Level Rod

, 1880
Reissued patent for an improvement in engineer's level which introduces a novel manner of marking the scale upon the face of the ...
Lynch, Michael L.
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source