Results 91 to 100 of about 739,614 (288)
The journey towards mRNA vaccine technology transfer: From knowledge to implementation
Coronavirus disease 2019 (COVID-19) vaccines were less accessible in low- and middle-income countries (LMICs) than in high-income countries during the pandemic. As a result, vaccine distribution initiatives such as COVID-19 Vaccines Global Access and the
Caryn Fenner +7 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
美國國家智財戰略並非單一的國家戰略,而是包括法律、政策與戰略,其涉及廣泛的行政機構和部門,以確保政府的努力集中且協調一致。而國家智財保護戰略主要的目的在保護美國境內與海外的智慧財產權。以往美政府各部門各有不同的智慧財產權政策與執法行動,但在2008年美國國會通過的「智慧財產資源及機構優先法案」(Prioritizing Resources and Organization for Intellectual Property Act)規定下制定了「智慧財產執法聯合戰略計畫」(Joint Strategic
黃孝怡 Hsiao-Yi Huang
doaj
Patent for a well drill wrench that improves upon William Ellinger's patent 1,327,379, issued January 6, 1920. This improvement eliminates friction between the rotatable and stationary parts of the wrench and ensures that the rotatable part is fully ...
Ellinger, William H.
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source

