Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Thrombus-in-Transit Across a Patent Foramen Ovale: Echocardiographic Recognition and Multimodality Management of a Fatal Paradoxical Event. [PDF]
Ramalingam A +4 more
europepmc +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Quadruple-Chamber Clot in Transit Traversing a Patent Foramen Ovale: Successful Percutaneous Mechanical Thrombectomy. [PDF]
Mehringer M, Massey B, Ali M, Clark B.
europepmc +1 more source
Who gets connected? Open government data and access to intercity innovation networks. [PDF]
Liu Y.
europepmc +1 more source
Hidden burden of malaria in pregnancy in hard-to-reach areas of Odisha, India: challenges to elimination and the case for integrating molecular surveillance. [PDF]
Sandeepta S +10 more
europepmc +1 more source
Historical Trends in Intraocular Lens Innovation Through an Analysis of United States Patents, 1972-2000. [PDF]
Mason E, Lin T, Margo CE.
europepmc +1 more source
Zero-fluoroscopy, intracardiac echocardiography-only patent foramen ovale closure in early pregnancy: a case report. [PDF]
Jo S, Kim TH, Lee YJ, Yun K, Kim JS.
europepmc +1 more source
Increasing competition in pharmaceutical tenders: Patents, treatment guidelines, and centralised procurement of Hepatitis C drugs in Brazil. [PDF]
Mercadante E.
europepmc +1 more source

