Results 271 to 280 of about 1,745,820 (365)

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Long-term effect of neoadjuvant denosumab treatment in high-risk early breast cancer (GeparX). [PDF]

ESMO Open
Link T, Reinisch M, Just M, Untch M, Filmann N, Stötzer O, Denkert C, Bjelic-Radisic V, Wimberger P, Thill M, Rhiem K, Huober J, Solbach C, Hanusch C, Engels K, Fasching PA, Schneeweiss A, Nekljudova V, Holtschmidt J, Blohmer JU, Loibl S.   +20 more
europepmc   +1 more source

External Patent Exploitation in a Non-Coercive way: A case study on a multinational operating firm

, 2014
Markus Eriksson
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Patent Foramen Ovale in Children: A Review of Epidemiological Characteristics, Natural Course, and Intervention Strategies. [PDF]

Children (Basel)
Wang C, Ma L, Jin J, Shi Z.
europepmc   +1 more source

The Case for the Coalition for Affordable Drugs: Hedge Funds Should Be Able to Challenge the Validity of Biotechnology Patents Using Inter Partes Review Despite Their Mixed Motives

, 2016
Jennifer Robichaux
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Patente / Patents

Tenside Surfactants Detergents, 1997
  +5 more sources

Integrating single-cell biophysical and transcriptomic features to resolve functional heterogeneity in mantle cell lymphoma. [PDF]

Sci Adv
Zhang Y, Debaize L, Langenbucher A, Weekes J, Vogiatzi I, Miettinen TP, Zhang M, Sumpena E, Liu H, Duquette SM, Hackett L, Zhang J, Baghiyan S, Redd RA, Aryee M, Davids MS, Kim AI, Ryan CE, Weinstock DM, Manalis SR, Murakami MA.   +20 more
europepmc   +1 more source

A Critical Analysis of the Proposed National Patent Board

, 1998
Richard P. Cusick, Kevin M. Flowers, Matt A. Mayer, David W. Poirier   +3 more
openalex   +1 more source