Results 261 to 270 of about 26,374,183 (352)

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Blood activating and stasis removing Chinese patent medicine in perioperative period of PCI for myocardial infarction: a protocol for a systematic review and Bayesian network meta-analysis of randomized controlled trials. [PDF]

Syst Rev
Wang YB, Cao Z, Liu C, Zhang C, Yang Z, Huang Q, Yan S, Ren X, Jin Y, Shang H, Brignardello-Petersen R.   +10 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Knowledge flows from science to AI technology: Identifying core and brokerage technological roles. [PDF]

PLoS One
Lee S, Hur J, Hwang J, Kogler DF, Kim K.
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Link Prediction of Green Patent Cooperation Network Based on Multidimensional Features. [PDF]

Entropy (Basel)
Yang M, Gao X, Ye Y, Liu J.
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Analytical Framework to Navigate Microalgae-Based Product Development-Aligning Commercialization and Regulatory Pathways. [PDF]

Mar Drugs
Tenzin G, Schipper K, Rathore H, Shah H, Brea E, Hankamer B, Hine D.   +6 more
europepmc   +1 more source

Retinal nerve fibre layer optical texture analysis: retinal nerve fibre bundle defect patterns and the extent of macular involvement across different stages of glaucoma. [PDF]

Br J Ophthalmol
Kamalipour A, Moghimi S, Khosravi P, Tansuebchueasai N, Camp AS, Vasile C, Adelpour M, Gunasegaran G, Kashaf MS, Nishida T, Zangwill LM, Lam AKN, Leung CK, Weinreb RN.   +13 more
europepmc   +1 more source

TB vaccine development: monitoring international patent filings to anticipate access challenges. [PDF]

Front Public Health
Pignataro MF, Scopel CT, Bacigalupo ML, Frick M, Kondratyuk S, Chaves GC.   +5 more
europepmc   +1 more source