Results 151 to 160 of about 19,095 (287)

The patent landscape in the field of stem cell therapy: closing the gap between research and clinic. [PDF]

open access: yesF1000Res, 2022
Hernández-Melchor D   +2 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

The Impact of “Patent Trolls” on Patent Law and the Legal Landscape of the United States [PDF]

open access: yes, 2009
In “An Industrial Property Rights Strategy for Europe“ the European Commission has mentioned “patent trolls” as a U.S. phenomenon connected with “poor quality [patent] rights.” However, the phenomenon cannot be explained solely by a poor level of work by
Trimble, Marketa
core  

The Race to Replace PDE5i: Recent Advances and Interventions to Treat or Manage Erectile Dysfunction: Evidence from Patent Landscape (2016-2021). [PDF]

open access: yesJ Clin Med, 2022
Islam MM   +13 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Patent Landscape of Helminth Vaccines and Related Technologies [PDF]

open access: yes, 2013
Executive Summary This report focuses on patent landscape analysis of technologies related to vaccines targeting parasitic worms, also known as helminths.
Michaud-King, Jillian   +4 more
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Brain Drain or Brain Bank? The Impact of Skilled Emigration on Poor-Country Innovation [PDF]

open access: yes
The development prospects of a poor country depend in part on its capacity for innovation. The productivity of its innovators depends in turn on their access to technological knowledge. The emigration of highly skilled individuals weakens local knowledge
Devesh Kapur, Ajay Agrawal, John McHale
core  

RETRACTED: BIO-SENSORY TECHNOLOGIES: GLOBAL DRIVERS IN THE DEVELOPMENT OF THE FIELD DEVELOPMENT

open access: yesEkonomika Nauki, 2016
RETRACTED ARTICLEThe article presents the results of multi-criteria patent analysis, which describes certain features of the development in the technological field of «bio-sensory devices for measuring physiological indexes» at its current stage.
V. G. Zinov, O. V. Cherchenko
doaj  

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