Results 31 to 40 of about 724 (203)

Importance of Public Interests in Patent Law

open access: yesBulletin of Kharkiv National University of Internal Affairs, 2021
The article is focused on studying and explaining the legal nature and content of public interests from point of view оf the patent protection system in the context of globalization processes.
O. V. Pikhurets, A. O. Pikhurets
doaj   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Recent legal developments from a nanotechnology perspective

open access: yesNanotechnology Reviews, 2012
With the recent major changes to the patent law system, it is more important than ever for nanotechnology-based companies to reevaluate their patent strategy.
Thiessen Rose, Lozan Vladimir
doaj   +1 more source

Nanotechnology – New Challenges for Patent Law?

open access: yesSCRIPTed: A Journal of Law, Technology & Society, 2009
After the advent of IT and genetic engineering, patent law now faces another challenge: nanotechnology. Being a hybrid of chemistry and engineering, nanotechnology holds some peculiarities that cause special problems for patent law.
Herbert Zech
doaj   +1 more source

Artificial intelligence in healthcare: possibilities of patent protection

open access: yesФармакоэкономика, 2021
The article provides an overview of the advantages and issues associated with the use of artificial intelligence (AI) and machine learning (ML) in medicine.
T. N. Erivantseva, Yu. V. Blokhina
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

PHARMACEUTICAL CO-CRYSTALLS. FEATURES OF ASSESING THE PATENTABILITY

open access: yesРазработка и регистрация лекарственных средств, 2019
In connection with the latest achievements of the theoretical crystallography the question of a potential patentability of new co-crystals of the known substances, as well as the estimation of their novelty and inventive step, becomes more and more ...
S. A. Sinchenko
doaj  

Istiglâlu Barâati al-Ikhtirâ’ fî al-Qânûn al-Indûnîsî Dirâsah Fiqhiyah Taqwîmiyah

open access: yesAl-Ihkam: Jurnal Hukum dan Pranata Sosial, 2020
Patent has a prominent place in people’s nowadays lives as it becomes the main mover of their advancement as well as a barometer of a nation’s development and treasure.
Husnul Haq, Arif Ali Arif
doaj   +1 more source

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