Results 151 to 160 of about 2,744,703 (304)
PROPOSED UNIFIED PATENT LITIGATION SYSTEM IN EU
Strani pravni život, 2012 The paper deals with the proposed Unified Patent Litigation System in EU. After introductory notes on the reasons for proposing this system, the first part of the article is dedicated to the European Patent Court.
Jelena Ćeranić
doaj
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
The Pharmaceutical Patent Protection Impact on Indonesia Drugs Price
Mimbar Hukum, 2012 This paper examines the pharmaceutical patent protection impact on Indonesian drugs price. As patent owner, companies could set high price for their drugs. However, such condition limits the access of the poor from patented drugs.
Tomi Suryo Utomo
doaj
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
An Empirical Review of Key Glucose Monitoring Devices: Product Iterations and Patent Protection. [PDF]
J Diabetes Sci TechnolDarrow JJ +3 more
europepmc +1 more source
Economic Growth and Patent Policy: Quantifying the Effects of Patent Length on R&D and Consumption [PDF]
Is the patent length an effective policy instrument in stimulating R&D? This paper develops a generalized variety-expanding growth model and then calibrates the model to the aggregate data of the US economy to analyze the effects of extending the patent ...
Chu, Angus C.
core
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Does Intellectual Property Protection Spur Technological Change [PDF]
Of the diverse factors motivating technological change, one factor that has received increasing attention in the recent past has been the protection of intellectual property rights.
Robert Evenson, Sunil Kanwar
core