Results 181 to 190 of about 2,744,703 (304)

Industrializing traditional medical knowledge in China: an integrated governance framework for addressing institutional fragmentation. [PDF]

Front Public Health
Wang Y, Xu K, Hua D.
europepmc   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Originality, Authorship, and Accountability in AI-Enabled Pharmaceutical Design. [PDF]

Clin Pharmacol Drug Dev
Hubbard MF, M Issa A, Fossler MJ.
europepmc   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Enhancing early-stage breakthrough technology identification: A CatBoost model optimized with the SABO algorithm. [PDF]

PLoS One
Lei M, Yu Y.
europepmc   +1 more source

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

FEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller, Jana Bleher, Birgit Weinberger, Lourdes Rocamora‐Reverte   +3 more
wiley   +1 more source

Clinical Evidence and Mechanistic Plausibility of Chinese Patent Medicines for Sepsis: An Evidence Map. [PDF]

J Inflamm Res
Liu Q, Zheng M, Wang Z, He Y, Xu J, Wang W, Sun X.   +6 more
europepmc   +1 more source

Guardians at the gate: patent protection for therapeutic monoclonal antibodies--part 1. [PDF]

MAbs, 2009
McCabe KW.
europepmc   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Patent Adaptation and the Construction of Special Rights: The Evolution of the EU's Animal Variety Protection System and China's Path Forward. [PDF]

Animals (Basel)
Zhou X, Zhang W, Zhang Z, Cheng B.
europepmc   +1 more source