Results 121 to 130 of about 202,256 (287)

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

open access: yesAdvanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett   +7 more
wiley   +1 more source

Ciencia, tecnología e innovación para el desarrollo y la cohesión social. Programa iberoamericano en la década de los bicentenarios [PDF]

open access: yes, 2016
La historia científica iberoamericana indica que nuestros países han producido menos premios Nobel en ciencias que varias de las universidades más prestigiosas del mundo desarrollado, y que nuestros escasos premios Nobel se concentran en pocos países ...
Anlló, Guillermo   +7 more
core  

Copolymers of Poly(Butylene Trans‐1,4‐Cyclohexanedicarboxylate)/Pripol as New Biomaterial Platform for Small Diameter Vascular Graft

open access: yesAdvanced Healthcare Materials, EarlyView.
Electrospun tubular scaffolds from novel PBCE‐based copolyesters and blends were designed as candidates for small‐diameter vascular grafts. They combine defect‐free architecture, blood‐compatible surfaces, and mechanical properties comparable to native vessels.
Edoardo Bondi   +7 more
wiley   +1 more source

Uso da informação contida em patentes nos países em desenvolvimento

open access: yesCiência da Informação, 1984
Uso da informação técnica contida na documentação de patentes, com especial ênfase para os países em desenvolvimento. Descrição das principais vantagens desse uso. Funções legal, econômica e técnica das patentes.
Vânia Maria Rodrigues Hermes de Araújo
doaj  

Why Did Corporations Patent in Spain? Some Historical Inquiries [PDF]

open access: yes
In this paper we will explore how international corporations used the Spanish patent system in the late nineteenth century and the first decades of the twentieth century in order to discover what the actual effects of its apparent weakness were.
Saiz, Patricio
core  

Bifunctional Surfaces With Immobilized Antibodies and Bioactive Peptides Mediate Selective Capture and Proliferation of Endothelial Colony‐Forming Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
A tunable bifunctional surface is developed by combining Fc‐binding peptides and RGD motifs to present oriented antibodies alongside integrin‐mediated signaling. The platform selectively captures endothelial colony‐forming cells while promoting their adhesion and proliferation.
Hugo A. Level   +5 more
wiley   +1 more source

Patentes sobre los genes BRCA-1 y BRCA-2: El caso Myriad [PDF]

open access: yes, 2011
El número de patentes sobre materiales biomédicos y procesos, como líneas celulares, métodos de replicación y pruebas genéticas está aumentando día a día.
Belli, Laura Florencia
core  

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

open access: yesAdvanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan   +13 more
wiley   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

open access: yesAdvanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang   +4 more
wiley   +1 more source

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