Results 31 to 40 of about 81,010 (209)

Associations of parental reproductive age and elevated blood pressure in offspring: An observational study

Frontiers in Pediatrics, 2023
BackgroundIncreased parental reproductive age has been a social trend around the world, and elevated blood pressure in children leads to an approximately two-fold increased risk of hypertension in adulthood.
Rui Deng, Ke Lou, Siliang Zhou, Xingxiu Li, Bin Dong, Jun Ma, Jie Hu   +6 more
doaj   +1 more source

Advancing paternal age does not affect in-vitro fertilization (IVF) outcomes in a Saudi population

Middle East Fertility Society Journal, 2015
Objective: To evaluate the effect of paternal age on in-vitro fertilization (IVF) outcomes. Design: Retrospective cohort study. Setting: Reproductive Endocrinology and Infertility Unit.
Samaher Saud Alfaraj, Faisel Yunus
doaj   +1 more source

Effect of Paternal Age on Reproductive Outcomes of Intracytoplasmic Sperm Injection. [PDF]

PLoS ONE, 2016
The impact of paternal age on reproduction, especially using assisted reproductive technologies, has not been well studied to date. To investigate the effect of paternal age on reproductive outcomes, here we performed a retrospective analysis of 2,627 ...
Yixuan Wu, Xiangjin Kang, Haiyan Zheng, Haiying Liu, Qing Huang, Jianqiao Liu   +5 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Interaction between social behavior and paternal age in offspring of the same paternal mice

Neuropsychopharmacology Reports, 2022
Aim Previous studies reported that advanced paternal age (APA) may increase the risk of autism spectrum disorder (ASD) in offspring. However, effects of APA on behaviors have not been investigated in offspring of the same paternal mice. The present study
Miho Tanaka, Atsushi Sato, Hiroko Kotajima‐Murakami, Hirofumi Kashii, Yoko Hagino, Soichiro Ide, Kazutaka Ikeda   +6 more
doaj   +1 more source

Association Between Paternal Separation During Early Childhood and Pubertal Timing Among Girls Using Longitudinal Birth Cohort in Japan

Frontiers in Endocrinology, 2021
IntroductionPrevious studies have shown that paternal absence leads to earlier pubertal timing among girls in high-income countries. Despite the low divorce rate in Japan, paternal separation is commonly seen due to a unique corporation system, tanshin ...
Aomi Katagiri, Nobutoshi Nawa, Takeo Fujiwara   +2 more
doaj   +1 more source

A Novel KCNA1 Variant in a Patient With Tremor and Autism Spectrum Disorder Causes Mixed LOF/GOF Defects of Kv1.1 Channels

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Variants in KCNA1, encoding the Kv1.1 potassium channel, cause neurological disorders including episodic ataxia and developmental and epileptic encephalopathy. We identified a novel KCNA1 variant (A401T) in a 16‐year‐old patient with autism spectrum disorder, borderline intellectual disability, and tremor, without episodic ataxia or epilepsy ...
Juan Darío Ortigoza‐Escobar, Laura Marti‐Sánchez, Loreto Martorell, Giorgia Dinoi, Antonio Vittorio Buono, Annamaria De Luca, Antonella Liantonio, Paola Imbrici   +7 more
wiley   +1 more source

The effect of paternal age on offspring intelligence and personality when controlling for paternal trait level.

PLoS ONE, 2014
Paternal age at conception has been found to predict the number of new genetic mutations. We examined the effect of father's age at birth on offspring intelligence, head circumference and personality traits.
Ruben C Arslan, Lars Penke, Wendy Johnson, William G Iacono, Matt McGue   +4 more
doaj   +1 more source

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Association Between Paternal Age and Birth Weight in Preterm and Full-Term Birth: A Retrospective Study

Frontiers in Endocrinology, 2021
PurposeWhile it is well documented that maternal adverse exposures contribute to a series defects on offspring health according to the Developmental Origins of Health and Disease (DOHaD) theory, paternal evidence is still insufficient.
Yiting Mao, Yiting Mao, Chen Zhang, Chen Zhang, Yinyu Wang, Yinyu Wang, Yicong Meng, Yicong Meng, Lei Chen, Cindy-Lee Dennis, Jianzhong Sheng, Yanting Wu, Hefeng Huang, Hefeng Huang, Hefeng Huang   +14 more
doaj   +1 more source