Results 81 to 90 of about 15,401 (263)

PEK14: A Kinesin‐4 Necessary for Male‐Derived Fertility in Arabidopsis thaliana

Cytoskeleton, EarlyView.
ABSTRACT Of the 61 kinesins annotated in Arabidopsis thaliana, many are still without assigned function. Here, we have screened an insertional mutant library of Arabidopsis pollen‐expressed kinesins for fertility defects. Insertional mutants for three kinesins showed a significant reduction in seed set.
Isabella N. Mendes, Norman R. Groves, Jessica Z. Li, Lily N. Thompson, Brian J. Smith, Aman Y. Husbands, Iris Meier   +6 more
wiley   +1 more source

Molecular identification of pollen donor plants on a progeny of Cambona-4 female matrix of maté (Ilex paraguariensis St. Hil. – Aquifoliaceae) - DOI: 10.4025/actascibiolsci.v32i1.764

Acta Scientiarum: Biological Sciences, 2009
A progeny of Cambona-4, a female maté plant (Ilex paraguariensis) selected by its agronomical characteristics and mild flavor, was evaluated using RAPD markers in order to identify its male parents.
Rogério Luis Cansian, Altemir José Mossi, Marco Di-Luccio, Michel Luis Cechet, Marcio Mazutti, Sergio Echeverrigaray   +5 more
doaj   +1 more source

Epilepsy Phenotypic Spectrum of NUS1‐Related Disorder: A Case Series

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Epilepsy with myoclonic and atonic seizures (EMAtS), also known as Doose syndrome, accounts for 1%–2% of childhood epilepsies, and various genes have been implicated in causing this epilepsy syndrome. NUS1 encodes for Nogo‐B receptor (NgBR), which stabilizes the dehydrodolichyl‐diphosphate synthase complex in the endoplasmic ...
Saumel Ahmadi, Natalie Fulton, Michael Morrissey, Rebekah Landre, Stuart Tomko, Fumihiko Urano, Réjean M Guerriero   +6 more
wiley   +1 more source

PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature

Clinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou, Estella S. Poloni, José A.G. Agúndez, Raquel L.F. Teixeira, Erin C. Boone, Adalberto Rezende Santos, Michelle Whirl‐Carrillo, Katrin Sangkuhl, Teri E. Klein, Mariam R. Habil, Giannoulis Fakis, Rodney F. Minchin, David W. Hein, Sotiria Boukouvala, Andrea Gaedigk   +14 more
wiley   +1 more source

Affective Paternalism

In this commentary we expand on the special issue themes of applied affective science, ecologically valid data and application, and the need for transdisciplinary collaboration by discussing and exemplifying how affective science can inform behavioral public policy.
Daniel Västfjäll, Erkin Asutay, Gustav Tinghög   +2 more
openaire   +1 more source

Starving for Data: Eating Disorders Prevalence and Research Gaps in Southern Africa

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Studies reporting prevalence estimates of eating disorders in Southern Africa are scarce. To fill this gap, the present Research Forum reviews existing literature on the prevalence of eating disorders, including as assessed by clinical interviews, screeners, and self‐reported behaviors, among individuals in Southern Africa.
Bernou Melisse, Jojanneke M. Bijsterbosch, Lot Sternheim   +2 more
wiley   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Female Mate Choice in Wild Kenyan Blue Monkeys (Cercopithecus mitis)

Animals
Female mate choice may drive sexual selection, but discerning whether female behaviors reflect free expression of choice or responses to constraints can be difficult.
Sofia Schembari, Caitlin Miller, Su-Jen Roberts, Marina Cords   +3 more
doaj   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

THE RIGHT TO KNOW ONE’S BIOLOGICAL IDENTITY [PDF]

Challenges of the Knowledge Society, 2013
In the last decade, European Court of Human Right case-law evolution revealed a new component of the right to private life, protected by the Human Rights Convention, Article 8.
VERONICA DOBOZI
doaj