Results 41 to 50 of about 342,777 (290)

The functional integral formulation of the Schrieffer–Wolff transformation

New Journal of Physics, 2016
We revisit the Schrieffer–Wolff transformation and present a path integral version of this important canonical transformation. The equivalence between the low-energy sector of the Anderson model in the so-called local moment regime and the spin-isotropic
Farzaneh Zamani, Pedro Ribeiro, Stefan Kirchner   +2 more
doaj   +1 more source

An Integral-Equation-Based Variance Reduction Method for Accelerated Monte Carlo Simulations

Photonics, 2023
In this work, we introduce a novel variance reduction approach utilising the integral formulation of the radiative transfer equation to calculate the radiance in a planar symmetric slab geometry.
David Hevisov, Dominik Reitzle, André Liemert, Alwin Kienle   +3 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

On the Relation between Operator Constraint --, Master Constraint --, Reduced Phase Space --, and Path Integral Quantisation

, 2009
Path integral formulations for gauge theories must start from the canonical formulation in order to obtain the correct measure. A possible avenue to derive it is to start from the reduced phase space formulation.
Ashtekar A, Ashtekar A, Ashtekar A, Baratin A Flori C Thiemann T, Bojowald M Perez A, Buffenoir E, Dirac P A M, Dittrich B, Dittrich B, Engle J Han M Thiemann T, Fleischhack C, Fradkin E S Vilkovisky G A, Giesel K, Giesel K Hofmann S Thiemann T Winkler O, Giesel K Hofmann S Thiemann T Winkler O, Giesel K Tambornino J Thiemann T, Giesel K Thiemann T, Gitman D M, Giulini D, Glimm J, Haag R, Han M, Han M, Han M Thiemann T, Henneaux M, Hollands S Wald R, Muxin Han, Perez A, Ramond P, Reed M, Roeppstorff G, Rovelli C, Rovelli C, Rudin W, Scharf G, T Thiemann, Thiemann T, Thiemann T, Thiemann T, Thiemann T, Thiemann T, Wald R M   +41 more
core   +2 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Comment on gauge choices and physical variables in QED [PDF]

, 1994
We consider possible definitions of physical variables in QED. We demonstrate that the condition $\partial_i A_i$$=0$ is the most convenient one because it leads to path integral over physical components with local action. However, other choices, as $A_3=
D. V. Vassilevich, D. Vassilevich, J. Schwinger, L. D. Faddeev, L. D. Faddeev, M. Lavelle   +5 more
core   +3 more sources

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

A note on background independence in AdS3 string theory

Journal of High Energy Physics
In this note, we comment on the path integral formulation of string theory on M $$ \mathcal{M} $$ × S3 × T 4 $$ {\mathbbm{T}}^4 $$ where M $$ \mathcal{M} $$ is any hyperbolic 3-manifold.
Bob Knighton
doaj   +1 more source