Determination and Comparison of the Pathogen Spectrum Evaluated by Microbial Culture and Multiplex PCR During Bronchoscopy with Regard to Clinical Utility of Routine Bronchial Wash in Patients with Various Pulmonary Diseases [PDF]
Background/Objectives: Bronchial wash for microbiological cultivation and/or multiplex polymerase chain reaction (PCR) is often routinely performed during bronchoscopy independent of the indication for bronchoscopy.
Christopher Milacek +5 more
doaj +2 more sources
Pathogen spectrum and immunotherapy in patients with anti-IFN-γ autoantibodies: A multicenter retrospective study and systematic review [PDF]
BackgroundAnti-interferon-γ autoantibody (AIGA) positivity is an emerging immunodeficiency syndrome closely associated with intracellular infection in individuals without human immunodeficiency virus (HIV).
Ye Qiu +12 more
doaj +2 more sources
Regional Spondylodiscitis Disparities: Impact on Pathogen Spectrum and Patients. [PDF]
Background: Spondylodiscitis is an infectious disease affecting an intervertebral disc and the adjacent vertebral bodies and is often the complication of a distant focus of infection. This study aims to ascertain the regional and hospital-specific disparities in bacterial patterns and resistance profiles in spontaneous and iatrogenic spondylodiscitis ...
Pantel T +7 more
europepmc +3 more sources
Respiratory bacterial and viral pathogen spectrum among influenza-positive and influenza-negative patients [PDF]
Background Respiratory tract infections are a significant burden on public health worldwide, with influenza being a prominent viral infection. Although influenza is known to predispose individuals to secondary bacterial infections, the precise spectrum ...
Jing Shi +12 more
doaj +2 more sources
Respiratory Infection-Related Pathogens in the Pediatric Intensive Care Unit During 2019–2024 in Hubei, China [PDF]
Respiratory infections are a leading cause of hospitalization and mortality in children, and the pediatric intensive care unit (PICU) is a critical setting for managing severe cases.
Jiahui Chen +17 more
doaj +2 more sources
Pathogenic antibodies to AQP4: Neuromyelitis optica spectrum disorder (NMOSD) [PDF]
NMOSD is a rare but severe relapsing remitting demyelinating disease that affects both adults and children. Most patients have pathogenic antibodies that target the central nervous system AQP4 protein. This review provides an update on our current understanding of the disease pathophysiology and describes the clinical, paraclinical features and ...
Wright, Sukhvir K. +2 more
openaire +2 more sources
The Greater Mekong Subregion (GMS) is the epicenter of antimalarial drug resistance. We determined in vitro susceptibilities to 11 drugs of culture-adapted Plasmodium falciparum isolates from adjacent areas (Laiza and Muse) along the China–Myanmar border.
Mengxi Duan +15 more
doaj +1 more source
The broad spectrum of pathogenic autoreactivity
Self-reactive immune responses occur in autoimmune diseases and also in chronic inflammatory and metabolic diseases that are not generally considered as autoimmune diseases. How do the mechanisms of autoreactivity in the different settings overlap and how are they distinguished?
Santambrogio, Laura, Marrack, Philippa
openaire +2 more sources
Aetiological Characteristics of Infectious Diarrhea in Yantai City, Shandong Province, China in 2017
This study aimed to analyse the pathogenic spectrum and epidemiological characteristics of infectious diarrhea in Yantai City, Shandong Province, China and provide a reference for its prevention and control.
Zhenlu Sun +8 more
doaj +1 more source
Enterovirus A71 (EV-A71) inactivated vaccines have been widely inoculated among children in Kunming City after it was approved. However, there was a large-scale outbreak of Enteroviruses (EVs) infection in Kunming, 2018.
Hongchao Jiang +16 more
doaj +1 more source

