Results 11 to 20 of about 203,756 (262)

Immune deficiency: changing spectrum of pathogens [PDF]

Clinical and Experimental Immunology, 2015
Summary Current UK national standards recommend routine bacteriology surveillance in severe antibody-deficient patients, but less guidance exists on virology screening and viral infections in these patients. In this retrospective audit, we assessed the proportion of positive virology or bacteriology respiratory and stool samples from ...
Duraisingham, SS, Manson, A, Grigoriadou, S, Buckland, M, Tong, CYW, Longhurst, HJ   +5 more
openaire   +3 more sources

Pathogenic Yield of Genetic Testing in Autism Spectrum Disorder [PDF]

Pediatrics, 2020
BACKGROUND AND OBJECTIVES: Genetic testing is recommended for individuals with autism spectrum disorder (ASD). Pathogenic yield varies by clinician and/or patient characteristics.
Holly K, Harris, Georgios D, Sideridis, William J, Barbaresi, Elizabeth, Harstad   +3 more
openaire   +2 more sources

Pathogenetic characteristics of infectious diarrhea in Yantai City, Shandong Province, 2018–2019

Frontiers in Public Health, 2023
BackgroundAnalysis of the pathogenic spectrum, epidemiological characteristics and molecular epidemiological features of important pathogens of infectious diarrhea in Yantai City, Shandong Province, 2018–2019, were analyzed to provide a reference basis ...
Qiao Gao, Hong Liu, Weixia Yu, Zhaolin Wang, Ying Yang, Kai Guo, Zhenlu Sun   +6 more
doaj   +1 more source

Antimicrobial Resistance and the Spectrum of Pathogens in Dental and Oral-Maxillofacial Infections in Hospitals and Dental Practices in Germany

Frontiers in Microbiology, 2021
Data on microbiological profiles in odontogenic infections are scarce. This study aimed to analyze the spectrum of pathogens and antimicrobial resistance in clinical isolates from dental and oral-maxillofacial clinical settings in Germany. We analyzed 20,
Annika Meinen, Annicka Reuss, Niklas Willrich, Marcel Feig, Ines Noll, Tim Eckmanns, Bilal Al-Nawas, Robby Markwart, Robby Markwart   +8 more
doaj   +1 more source

In vitro susceptibility of Plasmodium falciparum isolates from the China-Myanmar border area to artemisinins and correlation with K13 mutations

International Journal for Parasitology: Drugs and Drug Resistance, 2019
Mutations in the Kelch domain of the K13 gene (PF3D7_1343700) were previously associated with artemisinin resistance in Plasmodium falciparum. This study followed the dynamics of the K13 polymorphisms in P.
Jie Zhang, Na Li, Faiza A. Siddiqui, Shiling Xu, Jinting Geng, Jiaqi Zhang, Xi He, Luyi Zhao, Liang Pi, Yanmei Zhang, Cuiying Li, Xi Chen, Yanrui Wu, Jun Miao, Yaming Cao, Liwang Cui, Zhaoqing Yang   +16 more
doaj   +1 more source

The Acetobacteraceae: Extending the Spectrum of Human Pathogens

PLoS Pathogens, 2006
Patients with chronic granulomatous disease (CGD) get recurrent infections with a variety of bacterial and fungal pathogens as a consequence of phagocyte defects in production of antimicrobial reactive oxygen metabolites. Patients with CGD often present with clinical syndromes, such as pneumonia or lymphadenitis, for which no credible pathogen is ...
David Fredricks, Lalita Ramakrishnan
openaire   +5 more sources

Phosphatase inhibitors BVT-948 and alexidine dihydrochloride inhibit sexual development of the malaria parasite Plasmodium berghei

International Journal for Parasitology: Drugs and Drug Resistance, 2022
Background: With the emergence of resistance to front-line antimalarials, there is an urgent need to develop new medicines, including those targeting sexual development. This study aimed to assess the activity of a panel of phosphatase inhibitors against
Xitong Jia, Fei Liu, Jie Bai, Yongzhe Zhang, Liwang Cui, Yaming Cao, Enjie Luo   +6 more
doaj   +1 more source

Asbestosis: Clinical Spectrum and Pathogenic Mechanisms

Experimental Biology and Medicine, 1997
Asbestosis is a diffuse pulmonary fibrotic process caused by the inhalation of asbestos fibers. Despite extensive investigations, the precise mechanisms regulating asbestos-induced lung damage are not fully understood. This review summarizes the important clinical manifestations and pathogenic mechanisms of asbestosis.
D W, Kamp, S A, Weitzman
openaire   +2 more sources

Subtilisin-like Pr1 proteases marking the evolution of pathogenicity in a wide-spectrum insect-pathogenic fungus [PDF]

Virulence, 2020
Subtilisin-like Pr1 proteases of insect-pathogenic fungi are a large family of extracellular cuticle-degrading enzymes that presumably determine a capability of hyphal invasion into insect hemocoel through normal cuticle infection, but remain poorly understood although often considered as virulence factors for genetic improvement of fungal potential ...
Ben-Jie Gao, Ya-Ni Mou, Sen-Miao Tong, Sheng-Hua Ying, Ming-Guang Feng   +4 more
openaire   +3 more sources

The role of metagenomic next-generation sequencing in the pathogen detection of invasive osteoarticular infection

International Journal of Infectious Diseases, 2022
Objectives: This study aimed to analyze the pathogenic bacteria spectrum in invasive and primary osteoarticular infection (IOI and POI) and compare the pathogen detection rate of metagenomic next-generation sequencing (mNGS) and microbial culture in IOI ...
Xinyu Fang, Yuanqing Cai, Xiaoqing Chen, Changyu Huang, Yiming Lin, Zida Huang, Chaofan Zhang, Ying Huang, Wenbo Li, Wenming Zhang   +9 more
doaj   +1 more source