Results 21 to 30 of about 203,756 (262)

Alexidine Dihydrochloride Has Broad-Spectrum Activities against Diverse Fungal Pathogens [PDF]

mSphere, 2018
The prevalence of fungal infections has seen a rise in the past decades due to advances in modern medicine leading to an expanding population of device-associated and immunocompromised patients. Furthermore, the spectrum of pathogenic fungi has changed, with the emergence of multidrug-resistant strains such as C.
Mamouei, Zeinab, Alqarihi, Abdullah, Singh, Shakti, Xu, Shuying, Mansour, Michael K, Ibrahim, Ashraf S, Uppuluri, Priya   +6 more
openaire   +4 more sources

Diagnostic value of metagenomic next generation sequencing of bronchoalveolar lavage fluid in immunocompromised patients with pneumonia

Frontiers in Cellular and Infection Microbiology
BackgroundMetagenomic next-generation sequencing (mNGS) enables simultaneous sequencing of DNA fragments for comprehensive pathogen identification.
Liu Xin, Xiaodan Jiao, Xiaowei Gong, Jing Yu, Jing Zhao, Jing Lv, Qixuan Feng, YaDong Yuan, Wensen Pan   +8 more
doaj   +1 more source

Pathogen spectrum of diarrheal disease surveillance in Fengxian District， Shanghai， 2013‒2023

Shanghai yufang yixue
ObjectiveTo investigate the pathogenic spectrum and epidemiological characteristics of diarrheal disease in Fengxian District of Shanghai, and to provide scientific basis for the prevention and control of diarrheal diseases.MethodsBasic information of ...
LIU Meihua, ZHUANG Yuan, XIE Xiaohong, ZHAO Hongwei, SHI Yuan, DING Lijuan, HU Yi, TAO Lixin   +7 more
doaj   +1 more source

Analysis of the Sputum Culture Spectrum of Children with Respiratory Tract Infection in Wuxi Between 2014 and 2021

Infection and Drug Resistance, 2023
Hong-Liang Jia,1 Jian Gao,2 Feng Ren,2 Yaping Ma1 1Department of Pediatrics, Affiliated Hospital of Jiangnan University, Wuxi, 214122, People’s Republic of China; 2Department of Clinical Laboratory, Affiliated Hospital of Jiangnan University, Wuxi ...
Jia HL, Gao J, Ren F, Ma Y
doaj  

A retrospective clinical and microbial analysis of 32 patients with bilomas

BMC Gastroenterology, 2019
Background Bilomas are defined collections of bile fluids mainly caused by iatrogenic injuries of the bile duct system. Owing to the infrequency of this disease, studies addressing bilomas are rare.
S. Würstle, A. Göß, C. D. Spinner, W. Huber, H. Algül, C. Schlag, R. M. Schmid, A. Weber, A. Obermeier, J. Schneider   +9 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Epidemic characteristics and analyses of pathogen spectrum of viral encephalitis in Hebei Province from 2022 to 2023

Shanghai yufang yixue
ObjectiveTo investigate the epidemiological characteristics and etiological distribution of viral encephalitis in Hebei Province.MethodsCase information for patients diagnosed with viral encephalitis at 6 sentinel hospitals in Hebei Province from 2022 to
CAI Yanan, WEI Yamei, HAN Zhanying, ZHANG Yanbo, ZHANG Xinyang, XU Yonggang, HAN Xu, LI Qi   +7 more
doaj   +1 more source

Climate-Driven Trends in Pathogen Spectrum of HFMD [PDF]

, 2020
Abstract Background: Pathogen spectrum is vital during infectious disease epidemics. However, the role of pathogen spectrum during hand, foot, and mouth disease (HFMD) epidemics and the major contributing factors remains unknown.Methods: HFMD cases from 2016 to 2018 in Guangzhou, China were collected.
Zhicheng Du, Yong Huang, Wayne R. Lawrence, Jianxiong Xu, Zhicong Yang, Jianyun Lu, Zhoubin Zhang, Yuantao Hao   +7 more
openaire   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source