Results 131 to 140 of about 1,584,489 (303)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Emergence of antibiotic-resistant pathogens in ancient deep-sea sediments predates anthropogenic antibiotic use

Environment International
The rapid escalation of antibiotic resistance of pathogenic bacteria has become a critical global public health threat. Despite the extensive use of antibiotics in medicine, debates on the origins of antibiotic-resistance pathogenic bacterium remain ...
Zhitao Wu, Xiaobo Zhang
doaj   +1 more source

Swainsona Formosa (G.Don) Joy Thomp. Solvent Extractions Inhibit the Growth of a Panel of Pathogenic Bacteria

, 2017
Introduction: Swainsona formosa is a legumous plant which is endemic to the arid inland regions of Australia. Several Swainsona spp. were valued by the first Australian for their antiseptic properties and were used traditionally to treat a variety of ...
Getmore Rumbudzai Chikowe, Cock, Ian Edwin, Lindiwe Nomathemba Mpala, Ian Edwin Cock, Chikowe, Getmore Rumbudzai, Mpala, Lindiwe Nomathemba   +5 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Screening for Inhibitor Bakteri for Pathogenic Bacteria in Groupers Culture in Banten and Lampung Waters

Makara Seri Sains, 2009
A research about screening of inhibitor bacteria for pathogenic bacteria in grouper culture was done during 2005 in Marine Microbiology Laboratory, Research Center for Oceanography LIPI. Inhibition test was done using paper disc method for three isolates
Julinasari Dewi, Ruyitno Nuchsin, Ariani Hatmanti   +2 more
doaj  

Development of a multiplex PCR assay for rapid and simultaneous detection of four genera of fish pathogenic bacteria

, 2014
Species of genus Aeromonas, Vibrio, Edwardsiella and Streptococcus are the most common fish pathogenic bacteria that cause economically devastating losses in aquaculture.
Zhang, Q. Q., Li, A. H., Zhang, D. F.
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Probiotics against pathogenic bacteria and cancer

Сибирский онкологический журнал
This review focuses on the role of probiotics as alternative prevention and treatment of cancer. In this regard, we discuss the alternative cancer biotherapeutic drugs including live or dead probiotics and their metabolites, such as short chain fatty ...
V. A. Belyavskaya, N. V. Cherdyntseva, N. V. Litviakov, A. A. Ponomaryova, E. V. Udut   +4 more
doaj   +1 more source