Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Study on the pathogenic factors of pathogenic streptococci
Nippon Saikingaku ZasshiStreptococcus pyogenes infects the human pharynx, causing pharyngitis and tonsillitis, and as secondary complications, it can lead to acute glomerulonephritis and rheumatic fever. In recent years in Japan, there has been a trend of increasing cases of severe invasive streptococcal infections, which involve soft tissue necrosis, shock, and multiple ...
openaire +2 more sources
Plant Pathology and Plant Pathogens
, 2020 An updated guide to plant pathogens and their management.
Lucas, J.A
core
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Correction: The Irish potato famine pathogen Phytophthora infestans translocates the CRN8 kinase into host plant cells. [PDF]
PLoS Pathogens, 2015 PLOS Pathogens Staff
doaj +1 more source
ScilifelabDataCentre/pathogens-portal: Release 2024-02-15
<h2>What's Changed</h2> <ul> <li>add zenodo badge by @LianeHughes in https://github.com/ScilifelabDataCentre/pathogens-portal/pull/1095</li> <li>update citation information, inc Zenodo badge by @LianeHughes in https ...
Kazi Jahurul Islam +21 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Correction: Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection. [PDF]
PLoS Pathogens, 2015 PLOS Pathogens Staff
doaj +1 more source