Results 131 to 140 of about 963,592 (267)

Clinical performance of the BioFire Blood Culture Identification 2 panel for microorganism species identification and resistance gene detection in blood culture-positive specimens. [PDF]

PLoS One
Naruse H, Watanabe N, Koyama S, Tanaka S, Taji Y, Ebihara Y.   +5 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Correction: Aggressive Chemotherapy and the Selection of Drug Resistant Pathogens. [PDF]

PLoS Pathogens, 2015
PLOS Pathogens Staff
doaj   +1 more source

Retrospective analysis of infectious agents in swine abortion materials in the years 2021 to 2023. [PDF]

Vet Res Commun
Bischoff H, Beumer M, Helmer C, Spiekermeier I, Buch JM, Hundehege C, Menke T, Humann-Ziehank E, Hennig-Pauka I.   +8 more
europepmc   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Retraction: The Downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 Axis and by Human Cytomegalovirus (HCMV) Associated Factors Allows the Activation of the HCMV Major IE Promoter and the Transition to Productive Infection.

PLoS Pathogens
PLOS Pathogens Editors
doaj   +1 more source

Correction: SslE elicits functional antibodies that impair in vitro mucinase activity and in vivo colonization by both intestinal and extraintestinal Escherichia coli strains. [PDF]

PLoS Pathogens, 2015
PLOS Pathogens Staff
doaj   +1 more source

Purulent Pericarditis Caused by Polymicrobial Periodontal Pathogens (<i>Tannerella forsythia, Fusobacterium nucleatum</i>, and <i>Porphyromonas gingivalis</i>): A Case Report and Literature Review. [PDF]

Infect Drug Resist
Wei BH, Da HJ.
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Etiology and Epidemiology of Acute Lower Respiratory Infections Among Hospitalized Pediatric Patients in Northeastern China: A Retrospective Study from 2023 to 2025. [PDF]

Infect Drug Resist
Zhao HY, Zhang SY, Wang R, Zhang XY, Wang XF.   +4 more
europepmc   +1 more source