Results 51 to 60 of about 1,834,556 (315)

Correction: A Large Collection of Novel Nematode-Infecting Microsporidia and Their Diverse Interactions with Caenorhabditis elegans and Other Related Nematodes. [PDF]

PLoS Pathogens, 2017
[This corrects the article DOI: 10.1371/journal.ppat.1006093.].
PLOS Pathogens Staff
doaj   +1 more source

Association between periodontal pathogens and systemic disease

Biomedical Journal, 2019
A growing body of literature suggests that there is a link between periodontitis and systemic diseases. These diseases include cardiovascular disease, gastrointestinal and colorectal cancer, diabetes and insulin resistance, and Alzheimer's disease, as ...
Fiona Q. Bui, C. Almeida-da-Silva, Brandon Huynh, A. Trinh, Jessica Liu, J. Arthur Woodward, Homer Asadi, D. Ojcius   +7 more
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A new antibiotic selectively kills Gram-negative pathogens

Nature, 2019
The current need for novel antibiotics is especially acute for drug-resistant Gram-negative pathogens1,2. These microorganisms have a highly restrictive permeability barrier, which limits the penetration of most compounds3,4.
Y. Imai, Kirsten J. Meyer, Akira Iinishi, Q. Favre-Godal, R. Green, S. Manuse, M. Caboni, Miho Mori, Samantha Niles, Meghan Ghiglieri, Chandrashekhar Honrao, Xiaoyu Ma, J. Guo, A. Makriyannis, Luis Linares-Otoya, Nils Böhringer, Z. Wuisan, H. Kaur, Runrun Wu, A. Mateus, Athanasios Typas, Mikhail M. Savitski, Josh L. Espinoza, Aubrie O’Rourke, K. Nelson, S. Hiller, N. Noinaj, T. Schäberle, A. D’Onofrio, K. Lewis   +29 more
semanticscholar   +1 more source

Pathogens Spillover from Honey Bees to Other Arthropods

Pathogens, 2021
Honey bees, and pollinators in general, play a major role in the health of ecosystems. There is a consensus about the steady decrease in pollinator populations, which raises global ecological concern. Several drivers are implicated in this threat.
A. Nanetti, L. Bortolotti, Giovanni Cilia   +2 more
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Antimicrobial-resistant pathogens associated with adult healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network, 2015–2017

Infection control and hospital epidemiology, 2019
Objective: Describe common pathogens and antimicrobial resistance patterns for healthcare-associated infections (HAIs) that occurred during 2015–2017 and were reported to the Centers for Disease Control and Prevention’s (CDC’s) National Healthcare Safety
Lindsey M. Weiner-Lastinger, Sheila Abner, J. Edwards, A. Kallen, M. Karlsson, S. Magill, D. Pollock, I. See, M. Soe, M. Walters, Margaret A. Dudeck   +10 more
semanticscholar   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Correction: Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility.

PLoS Pathogens, 2017
[This corrects the article DOI: 10.1371/journal.ppat.1006075.].
PLOS Pathogens Staff
doaj   +1 more source