Results 171 to 180 of about 840,940 (292)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Re-defining standards of care in resectable head and neck squamous cell carcinoma-lessons from KEYNOTE-689 and NIVOPOSTOP. [PDF]

Oncologist
Mehra S, Yom SS, Burtness B.
europepmc   +1 more source

Pathological Correlation between Number of Biopsies and Radical Surgery: Does It Make a Difference to Final Pathology?

, 2013
Tahir Qayyum, Jennifer M. Willder, Paul G. Horgan, Joanne Edwards, Mark A. Underwood   +4 more
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Physical Factors Associated With Stage Progression of Lumbar Spondylolysis: A Prospective Cohort Study in Male Adolescent Soccer Players. [PDF]

Orthop J Sports Med
Tsutsui T, Sakamaki W, Takei S, Ikegami N, Torii S.   +4 more
europepmc   +1 more source

Functional Dyspepsia and Gastroparesis in Tertiary Care are Interchangeable Syndromes With Common Clinical and Pathologic Features

, 2021
Pankaj J. Pasricha, Madhusudan Grover, Katherine P. Yates, Thomas L. Abell, Cheryl E. Bernard, Kenneth L. Koch, Richard W. McCallum, Irene Sarosiek, Braden Kuo, Jiande Chen, Robert J. Shulman, Linda Lee, James Tonascia, Laura Miriel, Frank A. Hamilton, Gianrico Farrugia, Henry P. Parkman, Pankaj J. Pasricha, Robert Bulat, Robert Burns, Guillermo Barahona Hernandez, Megan McKnight, Braden Kuo, April Mendez, Kyle Staller, Andrea H. Thurler, Christopher Vélez, Casey J. Silvernale, Henry P. Parkman, Zubair Malik, Alan H. Maurer, Amiya Palit, Richard W. McCallum, Irene Sarosiek, Natalia Vega, Denise Vasquez, Sean Connery, Karina Espino, Marvin I. Friedman, Thomas L. Abell, Abigail Stocker, Bridget Cannon, Lindsay McElmurray, Kelly Cooper, Catherine McBride, Kenneth L. Koch, Lynn Baxter, Anya Brown, Paula S. Stuart, Amirah Abdullah, William J. Snape, Nata DeVole, Karen Earle, Kjersti Kirkeby, Candice Lee, Mimi Lin, Doug Troyer, Anna Bakonyi, Robert J. Shulman, Bruno P. Chumpitazi, Liz Febo‐Rodriguez, John M. Hollier, Cynthia Bouette, Heather Charron, Samuel Nurko, Stephanie Wall, Madeline Kane, Kent C. Williams, Lina Yossef‐Salameh, Frederick W. Woodley, Gianrico Farrugia, Madhusudan Grover, Cheryl E. Bernard, José Serrano, Frank A. Hamilton, Sherry Hall, S. Jill James, Rebecca Torrance, James Tonascia, Margaret Adamo, Patricia Belt, J.A. Dodge, Michele Donithan, Milana Isaacson, Linda Lee, Jill Meinert, Laura Miriel, Emily P. Sharkey, Jacqueline Smith, Michael S. Smith, Jürgen Floege, Mark L. Van Natta, Annette Wagoner, Laura Wilson, Goro Yamada, Katherine P. Yates, Katherine Yates   +96 more
openalex   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Development and external validation of a prognostic nomogram for event-free survival in resectable non-small cell lung cancer after neoadjuvant chemoimmunotherapy. [PDF]

Front Oncol
Qu L, Sun W, Liu X, Di J, Wang S, Xiong Y.   +5 more
europepmc   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Brain-peripheral proteome crosstalk in Alzheimer's disease with and without diabetes mellitus. [PDF]

Alzheimers Dement
Yaskolka Meir A, Wang X, Tasaki S, Sarsani V, Buchman AS, Arnold SE, Bennett DA, Petyuk VA, Liang L, Capuano AW, Arvanitakis Z.   +10 more
europepmc   +1 more source