Results 211 to 220 of about 685,737 (292)

Decoding B-cell Signatures of Complete Pathologic Response to Perioperative Chemoimmunotherapy in Non-Small Cell Lung Cancer. [PDF]

Clin Cancer Res
Sierra-Rodero B, Gil-González Á, Molina-Alejandre M, Nadal E, Calvo V, Lázaro M, Insa A, Massuti B, Martinez Marti A, de Castro J, García Campelo R, González Larriba JL, Bernabé R, Dómine M, Ponce Aix S, Cobo M, Camps C, Reguart N, Bosch-Barrera J, Majem M, Aguilar A, Palmero R, Blanco Clemente M, Martín-López J, Muñoz-Viana R, Megías D, Gutiérrez-Escobedo JM, Martínez-Toledo C, Cruz-Bermúdez A, Provencio M.   +29 more
europepmc   +1 more source

Genitourinary Pathology [PDF]

Laboratory Investigation, 2016
openaire   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Moulage: "Lupus Erythematosus"

Dermatology Practical & Conceptual, 2011
Beatrix Patzak
doaj   +1 more source

Divergent Differentiation and Histologic Subtypes in Upper Tract Urothelial Carcinoma Demonstrate Distinct Patterns of Extraurothelial Recurrence. [PDF]

Eur Urol Open Sci
Wang B, Davis LE, Nandwana D, Siva J, Maina E, Weight CJ, Haywood S, Campbell S, Campbell R, Sindhani M, Abouassaly R, Olivares R, Berglund R, Stein R, Kaouk J, Alaghehbandan R, Bukavina L.   +16 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Diffusion lacunae and T2 dark bands in placenta accreta spectrum: MR-pathologic correlation. [PDF]

Acta Radiol Open
Fujii S, Iraha Y, Ozaki K.
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Adjuvant radiotherapy for patients with clinical T3-4 oral and oropharyngeal cancer who achieved major pathologic response after neoadjuvant immunochemotherapy and surgery: a propensity score-matched retrospective study. [PDF]

Front Immunol
Li M, Yang S, Liu L, Hu W, Yan S, Zhang Y, Du M, Gao X, Yang C, Zheng L, Chen C, Zhou J, Lu J, Song M, Chen S.   +14 more
europepmc   +1 more source