DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial. [PDF]
Veliparib combined with carboplatin (VC) was an experimental regimen evaluated in the biomarker-rich neoadjuvant I-SPY 2 trial for breast cancer. VC showed improved efficacy in the triple negative signature.
Berry, Don+20 more
core +2 more sources
Roles of lipocalin-type and hematopoietic prostaglandin D synthases in mouse retinal angiogenesis
Normal angiogenesis is essential for retinal development and maintenance of visual function in the eye, and its abnormality can cause retinopathy and other eye diseases. Prostaglandin D2 is an anti-angiogenic lipid mediator produced by lipocalin-type PGD
Daiki Horikami+8 more
doaj +1 more source
Endoscopic management of biliary complications after liver transplantation [PDF]
Objective: To retrospectively evaluate endoscopic treatmentoutcomes of biliary complications in post-liver transplants.Methods: The sample consisted of post-liver transplantationpatients referred to the Endoscopy Unit of Hospital Israelita AlbertEinstein,
Fernanda Prata Martins+2 more
doaj
A Family History of Lethal Prostate Cancer and Risk of Aggressive Prostate Cancer in Patients Undergoing Radical Prostatectomy. [PDF]
We investigated whether a family history of lethal prostate cancer (PCa) was associated with high-risk disease or biochemical recurrence in patients undergoing radical prostatectomy. A cohort of radical prostatectomy patients was stratified into men with
Cohen, Seth A+4 more
core +1 more source
Chronic toxicity of inhaled thymol in lungs and respiratory tracts in mouse model. [PDF]
Epinephrine HFA (Primatene® Mist) is a newly formulated asthma metered dose inhaler developed to replace the previous Primatene® Mist CFC. The formulation of Epinephrine HFA contains thymol, a substance recognized to be safe by the FDA.
Luo, Mary Z+3 more
core +2 more sources
Pathologic analysis of liver transplantation for primary biliary cirrhosis [PDF]
A retrospective histopathologic review of all pathologic specimens from 394 adult liver transplant patients was undertaken with clinical correlation to determine if primary biliary cirrhosis has affected the posttrans‐plant course compared to all other ...
Ballardini+25 more
core +1 more source
May-Thurner Syndrome, an Often Overlooked Cause of Deep Vein Thrombosis: A Case Report
Deep vein thrombosis (DVT) is a common medical condition, but the predisposing anatomical factors, which may be amenable to definitive treatment, are usually overlooked. Therefore, a high index of clinical suspicion is the key to early diagnosis.
Akhwand Shakeel Ahmad
doaj +1 more source
Pathology and biobanking [PDF]
Biobanks are units where high quality and long-term protection of biomaterials is maintained. This system, in which biological materials and data are systematically recorded and stored, is a unique resource for the study of the pathophysiology of disease, the development of diagnostic biomarkers, and working with human tissues for the potential ...
Kelten Talu, Canan+3 more
openaire +5 more sources
Diagnosis of venous incompetence inerectile dysfunction [PDF]
In 26 of 214 patients with erectile dysfunction and proved venous incompetence by cavernosography, an additional bidirectional Doppler ultrasound was performed also to demonstrate venous outflow disturbances. All except one leakage in the superficial and
Bähren, Wolfgang+5 more
core +1 more source