Results 41 to 50 of about 6,088 (212)

Vitrectomy in high myopia: a narrative review

International Journal of Retina and Vitreous, 2017
Pathologic myopia is associated with degenerative changes of the globe, especially at the posterior pole. Eyes affected by pathologic myopia have higher odds to undergo posterior segment surgery and, in those eyes, vitreoretinal surgery is challenging ...
Michele Coppola, Alessandro Rabiolo, Maria Vittoria Cicinelli, Giuseppe Querques, Francesco Bandello   +4 more
doaj   +1 more source

Myopia and associated pathological complications [PDF]

Ophthalmic and Physiological Optics, 2005
Abstract Besides the direct economic and social burden of myopia, associated ocular complications may lead to substantial visual loss. In several population and clinic‐based cohorts, case–control and cross‐sectional studies, higher risks of posterior subcapsular cataract, cortical and nuclear cataract in myopic patients were reported.
Seang-Mei, Saw, Gus, Gazzard, Edwin Chan, Shih-Yen, Wei-Han, Chua   +3 more
openaire   +2 more sources

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

Advances of optical coherence tomography in myopia and pathologic myopia [PDF]

Eye, 2016
The natural course of high-axial myopia is variable and the development of pathologic myopia is not fully understood. Advancements in optical coherence tomography (OCT) technology have revealed peculiar intraocular structures in highly myopic eyes and unprecedented pathologies that cause visual impairment. New OCT findings include posterior precortical
D S C, Ng, C Y L, Cheung, F O, Luk, S, Mohamed, M E, Brelen, J C S, Yam, C W, Tsang, T Y Y, Lai   +7 more
openaire   +2 more sources

Improving access to new technologies: An experiment with Kenyan input sellers

American Journal of Agricultural Economics, EarlyView.
Abstract Agrodealers play a critical role in rural economies, selling essential inputs for agricultural production, stocking new products, and providing farmers with technical advice. However, uncertainty can discourage them from stocking newer, less familiar products, limiting the availability of innovative technologies and leading to market failures ...
Sarah W. Kariuki, Francisca N. Muteti, Annemie Maertens, Michael Ndegwa, Hope Michelson, Mercy Mbugua, Jason Donovan   +6 more
wiley   +1 more source

Ocular and Systemic Findings in COL2A1 and COL11A1 Stickler Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Stickler syndrome is most commonly caused by variants in COL2A1 and COL11A1 genes. The purpose of this study was to describe genetic variants and phenotypes in COL2A1 and COL11A1 Stickler syndrome. We performed a retrospective genotype–phenotype evaluation of COL2A1 and COL11A1 Stickler syndrome subjects. Thirty‐two subjects with COL2A1 and 13
Aileen G. MacLachlan, Jessica A. Kraker, Denise J. Morgan, Lisa A. Schimmenti, M. Elizabeth Hartnett, Eileen S. Hwang   +5 more
wiley   +1 more source

Rapid and spontaneous resolution of hemorrhagic macular hole retinal detachment and subretinal hemorrhages in an eye with pathologic myopia: a case report

BMC Ophthalmology, 2020
Background To report a rare case of pathologic myopia in which a choroidal neovascularization (CNV) induced a hemorrhagic macular hole retinal detachment (MHRD), and then both the CNV and MHRD disappeared simultaneously in 5 days.
Taiju Ito, Tae Igarashi-Yokoi, Kosei Shinohara, Takeshi Yoshida, Kyoko Ohno-Matsui   +4 more
doaj   +1 more source

ADNP‐Related Helsmoortel–Van der Aa Syndrome: A Review of the Literature and Clinical Recommendations for Assessment and Monitoring

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman, Ana Kolevzon, Paige Siper, Tess Levy, Jeffrey M. Saland, Yitzchak Frank, Robert Rapaport, Kayla Kupietzky, William E. Bennett Jr, Bruce Gelb, Sandra Bedrosian Sermone, Alexander Kolevzon   +11 more
wiley   +1 more source

A Novel Splice Variant in ERGIC1 Causes Arthrogryposis Multiplex Congenita—Characterization Using Urine‐Derived Cells

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis multiplex congenita (AMC) is defined as the presence of joint contractures affecting at least two body regions at birth. Three different ERGIC1 variants have been reported in individuals with AMC. Here, we report on a 16‐year‐old male with a homozygous ERGIC1 c.250+1G>A variant that was classified as a variant of uncertain ...
Lauren Kerr, Paul McKay, Juliana Marulanda, Zenghui Wu, Reggie Hamdy, Sena Tavukcu, Noémi Dahan‐Oliel, Frank Rauch   +7 more
wiley   +1 more source

Machine Learning Approaches in High Myopia: Systematic Review and Meta-Analysis

Journal of Medical Internet Research
BackgroundIn recent years, with the rapid development of machine learning (ML), it has gained widespread attention from researchers in clinical practice.
Huiyi Zuo, Baoyu Huang, Jian He, Liying Fang, Minli Huang   +4 more
doaj   +1 more source