Results 51 to 60 of about 2,815,174 (287)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Association between attention and heart rate fluctuations in pathological worriers [PDF]

, 2016
Recent data suggests that several psychopathological conditions are associated with alterations in the variability of behavioral and physiological responses.
Amadori, Francesca, Dettori, Maria, Gazzellini, Simone, Mancini, Francesco, Napolitano, Antonio, OTTAVIANI, CRISTINA, Paoli, Barbara   +6 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Graphs of real functions with pathological behaviors

, 2016
This paper deals with constructions and properties of unusual function from R to R, as discontinuous additive functions and everywhere surjections.Comment: Soft Computing ...
Bernardi, Claudio
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Developing the Quantitative Histopathology Image Ontology : A case study using the hot spot detection problem [PDF]

, 2017
Interoperability across data sets is a key challenge for quantitative histopathological imaging. There is a need for an ontology that can support effective merging of pathological image data with associated clinical and demographic data.
Doyle, Scott, Gurcan, Metin, James, A., John, Overton, N., Tomaszewski, Ruttenberg, Alan, Smith, Barry   +6 more
core  

Content Analysis of General Practitioner Requested Lumbar Spine X-ray Reports [PDF]

, 2007
Aims and Background X-rays of patients with low back pain rarely show serious pathology but frequently reveal incidental age-related changes and always expose people to radiation.
Carr, Eloise C.J., Thompson, Paul W.
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Computer simulation of syringomyelia in dogs [PDF]

, 2018
Syringomyelia is a pathological condition in which fluid-filled cavities (syringes) form and expand in the spinal cord. Syringomyelia is often linked with obstruction of the craniocervical junction and a Chiari malformation, which is similar in both ...
AC Freeman, AR Brodbelt, B Williams, B Williams, B Williams, BA Martin, BA Martin, BA Martin, C Rusbridge, C Rusbridge, C Rusbridge, C Rusbridge, C Rusbridge, CA Schneider, CD Bertram, CD Bertram, CD Bertram, CD Bertram, CJ Driver, Clare Rusbridge, DJ Marino, DN Levine, EC Clarke, F Loth, Holger A. Volk, HS Chang, IM Vavasour, J Strahle, JD Heiss, JE Parker, Jelena Jovanovik, K Berkouk, K Chandler, KH Stoverud, LE Bilston, LE Bilston, M Heil, M Kim, M Perdiki, MA Stoodley, MJ Hezzell, N Alperin, NJ Alperin, NJ Fischbein, NS Elliott, NS Elliott, NSJ Elliott, NSJ Elliott, PW Carpenter, R Fric, Robert Lloyd, S Cerda-Gonzalez, S Cirovic, S Cirovic, S Heidari Pahlavian, S Loderstedt, S Yildiz, SJ Hemley, SP Knowler, SP Knowler, Srdjan Cirovic, TH Milhorat, TH Milhorat, W Kalata, WD Whetstone   +64 more
core   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source